摘要
应用家兔失血性休克模型，观察高渗盐／右旋糖肝液（ＨＳＤ）、高渗盐／甘露醇液（ＨＳＭ）及高渗醋酸盐／甘露醇（ＮＡＭ）对其血气、酸碱平衡的影响。结果表明：ＨＳＤ和ＨＳＭ组在治疗后６０ｍｉｎ动脉血ｐＨ，ＢＥ－Ｂ，ＨＣＯ进一步下降，醚中毒加重，而ＨＡＭ组血ｐＨ，ＢＥ－Ｂ，ＨＣＯ升高，与失血前差异无显著性（Ｐ＞０．０５）。表明ＨＡＭ治疗能减轻失血性休克所致酸中毒，在稳定失血性休克兔内环境方面起重要作用。
ighteen adult heaIthy male rabbits were hemorrhaged to shock and treated with hypertonic-hyperoncotic solutions in 3 groups(6/group):hypertonic saline/dextran(HSD),hypertonicsaline/mannitol(HSM),and hypertonic acetate/mannitol(HAM).The results indicated:HSDand HSM can further decrease the pH,BE-B,HCO of the artery blood and increase acidosis ofhemorrhagicshock in 60 mins after infusion of them. HAM increases the blood pH,BE-B,HCO to the level of rabbits before hemorrhagic shock,which shows that HAM can treat theacidosis and blood gas change of hemorrhagic shock rabbits and plays an important role in stabi-lizing the inner erivironment of hemorrhagic rabbits.
出处
《湖南医科大学学报》
CSCD
1996年第2期105-108,共4页
Bulletin of Hunan Medical University
