摘要
目的探讨研究心脏电机械标测系统(NOGA)对急性心肌梗死(AMI)患者存活心肌的标测。方法11例AMI患者持续性胸痛发作12 h内急诊入院,急诊行经皮冠状动脉介入治疗(PCI)后第7天分别进行NOGA标测、心脏超声及核素心肌显像测定。结果NOGA系统测定出梗死区域的单极电压(UVP)显著低于非梗死区域[(6.8±3.1)与(10.9±3.1)mV,P<0.01],同时梗死区域内膜下心肌短缩率(LLS)明显小于非梗死区域心肌[(4.3±3.5)与(10.4±5.5)%,P<0.01]。特征性曲线分析NOGA判断心肌存活状态的UVP界定值为8.0 mV(敏感性及特异性均为73%)。结论LLS与心肌核素扫描及心脏超声相关性良好,当UVP≥8.0 mV时提示心肌处于存活状态。
Objective To study electromechanical mapping(NOGA)in the assessment of myo cardial viability in patients with acute myocardial infarction(AMI). Methods 11 patients with AMI within 12 hours underwent immediate percutaneous coronary intervention(PCI)with balloon inflation and stent deployment standard echoeardiograph,ECT and NOGA were performed on the 7th day after PCI procedure. Results The mean unipolar voltage potential (UVP) value was ( 10. 9 ± 3.1 ) mV in normal segment and (6.8 ± 3.1) mV in infracted segment (P〈0.01), The linear local shortening (LLS)value was in the non-infarct segments(10. 4±5.5)% and (4. 3±3.5)% (P〈0. 01). The linear local shortening(LLS) value was in the non-infarct segments(10.4 ± 5.5) % and (4. 3 ±3. 5) % (P 〈0. 01)in the infarcted area. The characteristic curves revealed that the UVP value of 8. 0 mV was optimal for differentiating the viable myoeardium from the non-viable with a sensitivity or specificity of 73%. Conclusion The LLS is correlated well with ECT and echocardiographic assessment of myoear dial contractility. The myocardial viability is indicated by a reference value of 8. 0 mV or more.
出处
《江苏医药》
CAS
CSCD
北大核心
2005年第10期743-745,共3页
Jiangsu Medical Journal