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高压氧和神经妥乐平治疗痛性糖尿病神经病变的临床研究

Clinical Study of Painful Neuropathy Treatment with High Pressure Oxygen and Neurotropin
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摘要 目的评价高压氧和神经妥乐平联合应用对2型糖尿病痛性神经病变的疗效。方法41 例2型糖尿病痛性神经病变患者,随机分组对照研究,对照组20例,只以神经妥乐平治疗,治疗组21 例,给予高压氧与神经妥乐平联合治疗,共8周。结果治疗组的总有效率与对照组比较差异有显著性(P<0.01),神经传导速度改善的有效率也有明显的提高(P<0.01)。结论高压氧和神经妥乐平联合应用可明显改善2型糖尿病痛性神经病变的治疗效果。 Objective To probe the curative effect of high pressure oxygen uniting with neurotropin in treating painful neuropathy of type 2 diabetes. Methods 41 cases of patients with type 2 diabetes complicating painful neuropathy were divided into two groups, the control (20 cases) and the treatment group (21 cases). Patients in the control group only took neurotropin, and in the treatment group patients receive high pressure oxygen uniting with neurotropin for eight weeks. Results There was significant difference in total effective rate between two groups (P 〈 0. 01). The conduction velocity of nerve was raised in the treatment group (P 〈 0. 01). Conclusions High pressure oxygen uniting with neurotropin can obviously improve the curative effect of painful neuropathy of type 2 diabetes.
出处 《神经疾病与精神卫生》 2005年第3期184-186,共3页 Journal of Neuroscience and Mental Health
关键词 痛性神经病变 高压氧 神经妥乐平 Painful neuropathy High pressure oxygen Neurotropin
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参考文献7

  • 1李洁,李秀钧.糖尿病痛性神经病变的诊断和处理[J].国外医学(内分泌学分册),2004,24(2):90-92. 被引量:56
  • 2Orimo H. Nakamura T. Osawa N,el al. The effects of neurotropin tablet in the treatment to diabetic neuropathy[J]. Progress in Medicine(Jpn), 1989,9: 306- 311.
  • 3叶任高.内科学[M].第5版[M].北京:人民卫生出版社,2001.798-820.
  • 4陈阳美,林丽萍.神经传导速度对糖尿病周围神经病的诊断价值[J].临床神经电生理学杂志,2004,13(2):67-69. 被引量:18
  • 5Lacomis D. Small-fiber neuropathy[J]. Muscle Nerve, 2002,26:173-188.
  • 6Cameron NE,Eaton SE,Cotter MA,et al. Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy[J]. Diabetologia, 2001,44:1 973- 1 988.
  • 7Morita S. Takcoka Y. Imai H,et al. Differential action of nerve growth factor,cyclic AMP and neurotropin on PC12h cells[J].Cell Struct Funct, 1988,13: 227- 234.

二级参考文献17

  • 1Ametor AS,Barinov A,Dyck PJ,et al.The sensory symptoms of diabetic polyneuropathy are improved with alpha-lipoic acid:the SYDNEY trial.Diabetes Care,2003,26:770-776.
  • 2Cotter MA,Jack AM,Camoron NE.Effects of the protein kinase C beta inhibitor LY333531 on neural and vascular function in rats with streptozotocin-induced diabetes.Clin Sci,2002,103:311-321.
  • 3Hotta N,Toyota T,Matsuoka K,et al.Clinical efficacy of fidarestat,a novel aldose reductase inhibitor,for diabetic peripheral neuropathy:a 52-week multicenter placebo-controlled double-blind parallel group study.Diabetes Care,2001,24:1776-1782.
  • 4Lacomis D.Small-fiber neuropathy.Muscle Nerve,2002,26:173-188.
  • 5Gimbel JS,Richards P,Portenoy RK.Controlled-release oxycodone for pain in diabetic neuropathy:a randomized controlled trial.Neurology,2003,60:927-934.
  • 6Hirai A,Yasuda H,Joko M,et al.Evaluation of diabetic neuropathy through the quantitation of cutaneous nerves.J Neurol Sci,2000,172:55-62.
  • 7Watson CP.The treatment of neuropathic pain:antidepressants and opioids.Clin J Pain,2000,16:S49-S55.
  • 8Vinik A,Pittenger G,Barcus NI,et al.Topiramate improves C-fiber neuropathy and dysmetabolic syndrome in diabetes.J Peripher Nerv Syst,2003,8:201.
  • 9Yuen KC,Baker NR,Rayman G.Treatment of chronic painful diabetic neuropathy with isosorbide dinitrate spray:a double-blinded placebo-controlledcross-over study.Diabetes Care,2002,25:1699-1703.
  • 10Rayman G,Baker NR,Krishnan ST.Glyceryl trinitrate patches as an alternative to isosorbide dinitrate spray in the treatment of chronic painful diabetic neuropathy.Diabetes Care,2003,26:2697-2698.

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