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白血病需要综合治疗 被引量：3

Integrative Treatment of Leukemia
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摘要 通过分析目前白血病单一治疗方法学中的利与弊,可以得到一些重要的启示和思考,这些启示引导我们要用综合的手段去治疗白血病,并最终攻克白血病这一顽疾。 To analyze excellence and shortcoming of single therapeutic method in leukemia at present, we can get some important illumination and thought. It leads us to treat leukemia with synthetical means, and leukemia will be cured in the future.
作者 肖毅 刘文励
机构地区 华中科技大学同济医学院附属同济医院血液科
出处 《医学与哲学》 北大核心 2005年第09X期24-25,44,共3页 Medicine and Philosophy
关键词 白血病 治疗方法 启示 综合性 leukemia therapeutic method illumination synthesis
分类号 R-02 [医药卫生] R733.7 [医药卫生—肿瘤]
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参考文献7

  • 1BRENNER M K. Cure of leukemia[J]. Semin Hematol, 1999( suppl7):73-81.
  • 2KABORE A F, JOHNSTON J B, GIBSON S B. Changes in the apoptotic and survival signaling in cancer cells and their potential therapeutic implications[J]. Curr Cancer Drug Targets,2004,4(2):147 - 163.
  • 3OHNO R, ASOU N, OHNISHI K. Treatment of acute promyelocytic leukemia[J]. Leukemia, 2003,17(8) : 1454 - 1463.
  • 4LU PH, NEGRIN R S. A novel population of expanded human CD3+CD56+ cells derived from T cell with potient in vivo antitumor activity in mice with severe combined immunodeficiency[J ]. J Immunol, 1994,153(8) : 1 687 - 1 696.
  • 5周剑锋,黄伟,张瑶珍,刘文励.细胞周期检测点激酶Chk1和Chk2在急性白血病骨髓单个核细胞中表达的研究[J].华中科技大学学报（医学版）,2004,33(2):161-164. 被引量：3
  • 6BJORKSTRAND B, SVENSSON H, GOLDSCHMIDT H, et al. Alpha-interferon maintenance treatment is associated with improved survival after high - dose treatment and autologous stem cell transplantation in patients with multiple myeloma, a retrospective registry study from the European Group for Blood and Marrow Transplantation(EBMT) [J]. Bone Marrow Transplant, 2001 ,27(5) :511 - 515.
  • 7POWLES R, SIROHI B, TRELEAVEN J, et al. The role of posttransplantation maintenance chemotherapy in improving the outcome of autotransplantation in adult acute lymphoblastic leukemia [J]. Blood,2002,100(5):1641 - 1647.

二级参考文献5

  • 1Shigeishi H, Yokozaki H, Oue N et al. Increased expression of CHK2 in human gastric carcinomas harboring p53 mutations. Int J Cancer ,2002,99:58
  • 2Hirose Y, Berger M S, Pieper R O et al. Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells.Cancer Res, 2001,61:5843
  • 3Koniaras K, Cuddihy A R, Christopoulos H et al. Inhibition of Chk1-dependent G2 DNA damage checkpoint radiosensitizes p53 mutant human cells. Oncogene, 2001, 20:7453
  • 4Vahteristo P, Bartkova J, Eerola H et al. A Chek2 genetic variant contributing to a substantial fraction of familial breast cancer. Am J Hum Genet, 2002, 71:432
  • 5Matsuoka S, Nakagawa T, Masuda A et al. Reduced expression and impaired kinase activity of a Chk2 mutant identified in human lung cancer.Cancer Res,2001,61:5362

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医学与哲学
2005年 第09X期

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