摘要
35例中晚期肝癌病人利用左锁骨下动脉埋置的药盒,经肝动脉行长期间歇化疗灌注,采用的方案为F.A.D,即ADM60mgD1,5—FU0.5gD1—5,CDDP60mgD5,每四周重复一次,结果是一年生存率33.3％,最长一例至今已达一年半,化疗毒副作用也比经静脉的全身化疗轻。作者认为弥漫型肝癌和转移性肝癌是此一方法的良好适应症,对埋药盒的方法和并发症亦作了介绍。
35 patients of non-resectable PHC 23 cases, liver metastases 12 cases were treated with F. A. D. combined hepatic infusion chemotherapy using the following regimen: ADM 60mg Dl/4w shot, 5-Fu 0. 5 Dl-5/4w shot, CDDP 60mg D5/4w shot. In every case, the catheter was placed into the hepatic artery via the left subclavian artery and an implantable portal system was used for infusion. The results were as following: 11 cases (33. 3%) survived for more than 1 year with the range of 1 - 1. 5 years. The side effects such as bone marrow supression, gastroduodenal trouble was slighter than F. A. D. regimen via iv. For the long-term catheterization in the intermittent chemotherapy, the part-catheter system (PCS) is recommended. The technique required and complications generated from the implantation were introduced in this paper.
出处
《影像诊断与介入放射学》
1996年第1期1-3,共3页
Diagnostic Imaging & Interventional Radiology
关键词
肝癌
治疗
导管-药盒系统
Liver cancer Port-Catheter System Catheterization Hepatic artery infusion
