摘要
为评价联合检测大肠癌患者血清ｓＩＬ—２Ｒ与β２—ＭＧ的临床意义，以酶职双抗体夹心免疫法及放射免疫法对７０例大肠癌患者血清ｓＩＬ—２Ｒ与β２—ＭＧ的浓度进行了测定。发现大肠癌患者血清中二者浓度明显高于正常人，与Ｄｕｋｅｓ分期有明显相关性。根治术后其水平明显下降。提示：二者联合检测对大肠癌的辅助诊断、疗效评价、预后监测有指导意义，且具简便、无创的优点，可广泛应用于临床。
To evaluate the clinical significance of serum soluble interleukin 2 receptor(sIL-2R)and β_2-microglobulin(β_2-MG)in patients with colorectal carcima.Serum levers of slL-2R β_2-MGwere measured in 70 patients with colorectal carcinoma.The reasults indicated that the serum levers ofsIL-2R and β_2-MG were significantly higher in patients than those in normal control group(P<0.01). We found that the increase of slL-2R and β_2-MG is related with clinical stages(P<0.01).Thelevels of sIL-2R and β_2-MG were remarkably reduced after redical operation(P<0.01),otherwise,there were no singnificantly reduce in improbable operation group.It can be concluded that serum sIL-2R and β_2-MG Ievels are a new biological marker for the assessment of the stage,the response to medi-cal intervention and judging of prognosis in colorectal cancer.
出处
《泰山医学院学报》
1996年第2期117-119,共3页
Journal of Taishan Medical College
关键词
大肠癌
SIL-2R
Β2-MG
检测
slouble interleukin 2 recptor
colorectal carcinoma
β_2-microglobulin(β_2-MG)
