摘要
目的:观察多支冠脉病变并心功能不全患者经皮冠脉介入术(PCI)后部分血运重建的安全性和有效性.方法:56例多支血管病变的冠心病患者,男41例,女15例,平均年龄67±10岁,心功能Ⅱ～Ⅲ级,依自愿原则随机分为两组,介入治疗(PCI)组和单纯药物治疗(MT)组.两组常规应用抗心绞痛及抗心衰药物治疗.于治疗1个月、6个月、12个月分别行超声心动图检查评价心功能.结果:PCI组和MT组1年生存率分别为98%和89%,未发生Q波心梗者分别占96%和87%,两组间未再发作明显心绞痛者分别占82%和49%,与术前比,PCI组在术后1个月左室射血分数有所增加(P＜0.05),同时高于药物治疗组(P＜0.05).在6个月时进一步改善,1年与6个月无显著差异.而药物治疗组仅在治疗6个月后,左室射血分数方有改善.结论:该结果显示:PCI组与MT组相比,不完全血运重建对于冠脉多支病变伴心功能不全患者仍不失为积极有效的治疗手段,可以改善心功能,提高生存率,改善生活质量.
Objective： To observe the safety and efficiency concerning the partial blood-circulation-rebuilt of muhivessel coronary and heart failure patient after percutaneous coronary inter vention （PCI）. Methods ： 56 multivessel coronary patients （male 41 female 15）averagely aged 67 ±10 with heart function grade Ⅱ -Ⅲ randomly divided into two groups; PCI group and MT group. The two groups, treated with the routine method of anti-anginal and anti-heart failure drug, were examined separately within one month, six month and a year, with ultrasonic cardiogram to assess the heart function. Results ： The servival rates of PCI group and MT group were separately 98% and 89% ,and the rates Non- Q-wave myocardial infarction were separately 96 % and 87 %. The rates of no angina were separately 82 % and 49% between the two groups. Compared with pre-operation, The LVEF of PCI group increased one month after operation（P 〈 0.05） ,higher than that of MT group （ P 〈 0.05）. By the time of six months, the situation was further improved and there was no obvious difference between six month and one year. But LVEF of MT group was a little improved only after six months, of treatment. Conclusion ： The result shows that,compared between PCI group and MT group, partial blood-circulation rebuilt is still an efficient and positive treatment method as to the multivessel coronary and heart failure, it can improve heart function, raise servival rate and improve living quality.
出处
《河南医学研究》
CAS
2005年第3期252-253,共2页
Henan Medical Research
