摘要
对68例鼻恶性肿瘤病人进行血小板聚集试验,并以100例正常人和10例鼻良性肿瘤病人作对照.结果发现①恶性肿瘤中,治疗前组、复发组和远隔转移组血小板最大聚集率(MAR)均数高于正常组、良性肿瘤组和治疗后组(P<0.05);②治疗前组中MAR均数随肿瘤分期而增高.表明恶性肿瘤可引起血小板聚集增强.并就恶性肿瘤病人血小板聚集增强的机制.血小板在肿瘤生长、转移中的作用等进行讨论.还展望了血小板抑制剂在抗肿瘤的应用前景.
Platelet aggregation tests(PAgT) were performed in 68 patients with malignant tumor of the nose. 100 normal persons and 10 patients with benign tumor of the nose. The maximum aggregation rates (MAR ) of the platelets in pre-treatment group, recurring group and hematoge-nous metastatic group of the malignant tumor were all significantly higher than that of normal persons , patients with benign tumors and post-treatment group of malignant tumors ; the mean of MAR increased with the development of tumor stages. These results showed that malignant tumor of the nose may cause the increase of the platelet aggregation It is suggested that platelet aggregation inhibitor may be used as an adjuvant in antimetastatic and antitumor treatment.
出处
《临床耳鼻咽喉科杂志》
CSCD
1996年第4期208-210,共3页
Journal of Clinical Otorhinolaryngology
