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ras癌基因与肺癌 被引量:3

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摘要 ras癌基因与肺癌杨青综述刘学泽詹承烈审校一、癌基因概述癌基因(oncogene)是指在自然或实验条件下具有诱导细胞恶性转化的潜在活性基因。目前,在脊椎动物包括人类中已检测到近百种原癌基因。各种外源性因素,如辐射、化学致癌物、病毒等能使正常细胞中癌基...
作者 杨青 刘学泽
出处 《中华劳动卫生职业病杂志》 CAS CSCD 1996年第3期176-178,共3页 Chinese Journal of Industrial Hygiene and Occupational Diseases
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参考文献4

  • 1杨青,现代预防医学,1995年,22卷,193页
  • 2杨青,14th Conference on Occupational Health,1993年
  • 3覃杨,生物化学与生物物理进展,1992年,19卷,277页
  • 4You M,Proc Natl Acad Sci USA,1989年,86卷,3070页

同被引文献28

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  • 2[4]Keshava C, Keshava N, Zhou G, et al. Instability in silica - and cadmium chloride - transformed BALB/c - 3T3 and tumor cell lines by random Genomic amplified polymorphic DNA analysis[J]. Mutation Research, 1999, 425 (1): 117 - 123.
  • 3[6]Kathleen GH, Jerry PR, Bhalchanda AD, et al. GGT to GTT transversions in code 12 of the k - ras oncogene in the rat renal sarcomas induced with nickel subsulfide/iron are consistent with oxidative damage to DNA[J]. Cancer Res, 1992, 52(17) :4747 - 4751.
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  • 6Gruenert DC,Finkbeiner WE,Widdicombe Jh.Culture and transformation of human airway epithelial cells[J].Am J Physiol,1995,268:L347-360.
  • 7Osuke w,Masaaki N,Hirotaka O,et al.In vivo occurrence of p16 and p15 alterations preferentially in non-small cell lung cancer[J].Cancer research,1995,55(3),514-517.
  • 8Keshava C,Keshava N,Zhou G,et al.instability in silica- and cadmium chloride-transformed BALB/c-3T3 and tumor cell lines by random Genomic amplified polymorphic DNA analysis[J].Mutation Reserch,1999,425(1):117-123.
  • 9Kathleen GH,Jerry PR,Bhalchanda AD,et al.GGT to GTT transversions in code 12 of the K-ras oncogene in the rat renal sarcomas induced with nickel subsulfide/iron are consistent with oxidative damage to DNA[J].Cancer Res,1992,52(17):4747-4751.
  • 10Chang J,Watson WP,Randerath E,et al.Bulky DNA-adduct formation induced by Ni(II) in vitro and in vivo as assayed by 32P-postlabeling[J].Mutat Res,1993,291(2):147-159.

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