摘要
20多年来国内外相继开展了高渗盐水治疗休克的研究，特别是7．5％氯化钠的抗休克作用有了很多的报道，高渗盐溶液在失血性休克液体复苏中的应用越来越广泛，其抗休克效果在动物实验和临床应用中都得到了肯定，但也存在输入过程中出现血压下降，尿量减少的报道，对抗休克时所使用的剂量也存在一些争议。笔者就近年来应用高渗盐水抗休克的基础和临床研究进行如下综述，着重阐明高渗盐水抗休克的主要机制及临床应用的一些方法.
In about twenty years, the research of hypertonic saline as , esuscitation solution for hemorrhagic shock was made at home and abroad. Especially, the anti-shock effect of 7.5% NaCl solution was reported more often and the apply of hypertonic saline as a resuscitation solution was more and more wide, the incidence of anti-shock effect has been observed both in animals and patients. But there are still different views, such as the drop of blood pressure and amount of urine in the course of transfusion and the application dosage is controversial. The author summarized the status of recent studies on experimental and clinical of hypertonic saline as a resuscitation solution for hemorrhagic shock, the mechanism of antishock effect of hypertonic saline and the method of clinical use were emphasized.
出处
《世界急危重病医学杂志》
2005年第5期923-926,共4页
internationl journal of emergency and critical care medicine
关键词
盐溶液
高渗
休克
失血
Saline solution, hypertonic
Shock
hemorrhagic
