摘要
感染是多器官功能不全综合征（MODS）的主要诱因之一。目前较一致的观点是：感染诱发的炎症过程参与了MODS的形成与发展。而对于其导致MODS的病理变化特点及其可能的启动机制．存在不同的结论及假说。本期刊录的三篇研究生论文介绍了NF—κB——白介素（IL）家族通路中不同的炎症因子在感染以及MODS中的启动机制和监测意义。
Chronic heart failure （CHF） is a common complication of patients with heart dysfunction and of those suffering from various chronic illnesses. Although recently developed therapies revolutionized treatment of CHF, its morbidity and mortality is still very high and survival rate in 5 years is even lower than cancer. Recently the interest of investigators has been focused on immune mechanisms in the pathogenesis of CHF. There is increasing evidence that inflammatory cytokines play an important role in the development of heart failure. But the source and site of proinflammatory cytokines in CHF are not yet known. Endotoxin,
出处
《世界急危重病医学杂志》
2005年第5期888-890,共3页
internationl journal of emergency and critical care medicine
基金
本课题是王士雯院士牵头的973研究课题子课题的一部分.
