摘要
目的:比较非体外循环冠状动脉搭桥术(off-pump CABG)与体外循环冠状动脉搭桥术(on-pumpCABG)2种手术方式对心肌的损害。方法:将30例行冠脉搭桥病人分为off-pump组与on-pump组,观察2种手术方式围手术期(插管前和术后8、16、24、36、48、72、96 h)血清肌钙蛋白T(TNT)、肌酸激酶-同工酶(CK-MB)水平及术后心电图变化,并进行评价。结果:2组病人术前TNT、CK-MB均正常。术后各时间点TNT值监测:off-pump组3例(20%)、on-pump组12例(80%)升高,差异有统计学意义(P<0.05)。术后2组病人各时间点CK-MB均升高,off-pump组术后24 h达高峰,on-pump组术后36 h达高峰,峰值差异有统计学意义(P<0.05)。术后心电图监测未发现有新的Q波形成及ST-T改变。结论:off-pump CABG对心肌损伤较小。
Objective： To compare the myocardial injury of the off-pump CABG with on-pump CABG. Methods： To observe the changes of troponin T（TNT）, creatinine kinase isoenzyme（CK-MB） and ECG during the time of the surgery （before intubation and 8,16,24,36.48.72,96 h after operation） and evaluate the results. Results： TNT, CK-MB were all normal before surgery, Observing every time of TNT in two gropes after surgery, in 3 patients TNT were elevated in off-pump grope and 12 patients in on-pump grope, the difference had statistical significance （P〈0.05）, every time of CK-MB elevated in both groups after surgery, the peak level appeared 24 h in off-pump and 36h in on-pump after surgery. The peak difference has statistical significance （P〈0.05）. There were not new Q waves and the changes of ST-T after surgery. Conclusion： Compared with on-pump CABG, off-pump CABG has little myocardial injury.
出处
《新疆医科大学学报》
CAS
2005年第8期734-736,共3页
Journal of Xinjiang Medical University
