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庆大霉素耳毒性的临床听力学观察 被引量:1

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摘要 目的观察庆大霉素耳毒性的临床听力学特点。方法48名志愿者,静脉用硫酸庆大霉素16万单位日,共5~8天,总剂量80~128万单位,于用药前、用药最后1天、停药后1月进行纯音测听、听性脑干反应测试,并对结果进行方差分析。结果治疗最后1天,纯音测听高频听力减退者占17.5%,用药后1月占8.9%;ABR测试治疗前后无差异。结论庆大霉素耳中毒早期主要引起高频听力减退。
出处 《听力学及言语疾病杂志》 CAS CSCD 2005年第5期372-373,共2页 Journal of Audiology and Speech Pathology
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