摘要
目的评价厚朴排气合剂治疗腹部非胃肠吻合术后早期肠麻痹(气滞证)的有效性及安全性。方法采用随机对照多中心临床试验的方法,试验组术后6 h口服厚朴排气合剂50 mL,4 h后再服厚朴排气合剂50 mL;对照组术后6 h口服西沙比利片10 mg,4 h后再服西沙比利片10 mg。疗程24 h。试验组327例,对照组108例。结果中医症状疗效比较:试验组94.80%,对照组87.96%。试验组明显优于对照组(P<0.05)。临床疗效:试验组94.19%,对照组83.33%。试验组明显优于对照组(P<0.05)。结论厚朴排气合剂治疗腹部非胃肠吻合术后早期肠麻痹疗效显著,未见明显不良反应。
Objective To evaluate the effect and safety of Houpo Paiqi Mixture （HPM） in treating early enteroparalysis elassified as Qi-stagnation syndrome after abdominal non-gastrointestinal operation. Methods A multi-center, randomized, controlled study was carried out. The treatment group （n = 327 ） was treated with HPM （50 mL P,O, 6 and 10 hours after operation ） and the control group （n=108） with eisapride tablets （ 10 mg P,O, 6 and 10 hours after operation ） . The course of treatment lasted 24 hours. Results A significant difference （P 〈 0. 05 ） was found in effective rate in relieving symptoms and signs （94. 80 % in treatment group and 87. 96 % in control group ） and in total clinical effective rate （94. 19 % in treatment group and 83. 33 % in control group ）. The effect in treatment group is superior to that in control group. Conclusion HPM is effective and safe in treating early enteroparalysis after abdominal non-gastrointestinal operation.
出处
《中药新药与临床药理》
CAS
CSCD
2005年第5期383-384,共2页
Traditional Chinese Drug Research and Clinical Pharmacology
关键词
厚朴排气合剂
早期肠麻痹
气滞证
中药疗法
Houpo Paiqi Mixture
Early enteroparalysis
Qi-stagnation syndrome
TCD therapy
