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炎症反应在脑出血后细胞凋亡中的作用 被引量：3

The Role of Inflammation in Apotosis After Intracerebral Hemorrhage
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摘要 脑出血后血肿周围区可发生继发性损伤。最近的研究表明,血肿周围区出血后神经细胞的死亡,其中炎症反应在脑出血后细胞凋亡中起着十分重要的作用,包括白细胞和小胶质细胞渗出、多种细胞因子的表达以及基质金属蛋白酶和凝血酶的释放。对脑出血后炎症反应的作用进行研究,有望找到新的脑出血治疗的切入点。 The secondary injuries may occur in the perihematoma region after intracerebral hemorrhage（ICH）. Recent studies suggested cell death in the perihematoma region may involve apoptosis, in which inflammatory reaction may play an important role, including the infiltration of leukocytes and microglia, the expression of cytokines, as well as the release of matrix metalloproteinases and thrombin. The study of the role of inflammation may find a new approach for the treatment of ICH.
作者 皇甫赟 吴成翰
机构地区 福建中医学院 福建省第二人民医院神经内科
出处 《国外医学（脑血管疾病分册）》 2005年第7期529-532,共4页 Foreign Medical Sciences Cerebrovascular Diseases
关键词 炎症反应 脑出血 细胞凋亡 脑出血治疗 基质金属蛋白酶 血肿周围区 继发性损伤 小胶质细胞 神经细胞 细胞因子 inflammation intracerebral hemorrhage apoptosis
分类号 R743.3 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献30

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二级参考文献14

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共引文献7

同被引文献28

引证文献3

二级引证文献22

国外医学（脑血管疾病分册）
2005年 第7期

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