摘要
目的探讨阴囊阴茎Paget's病的临床特点和诊治方法.方法对13例阴囊阴茎Paget's病患者的临床、病理资料以及治疗随访情况进行回顾性分析.结果所有13例均经手术治疗,施行局部扩大的病灶切除术;10例用剩余的阴囊皮肤覆盖创面,3例行游离植皮术.其中1例在病程中复发3次,均经手术切除,现随访6个月无复发;其它12例经一次手术后随访2～64月无复发.3例腹股沟淋巴结肿大者有1例系癌转移.所有病例未发现远处转移.结论本病的诊断主要依靠病理;局部扩大的病灶切除术是治愈的关键,对于皮肤缺损可用阴囊皮瓣及游离植皮的方法覆盖;腹股沟淋巴结肿大不一定是癌转移;切除范围不够、瘤细胞侵入真皮层、病灶中有腺癌成分是复发的主要原因.
Objective To probe into the clinical behavior, diagnosis and treatment of Paget＇s disease of the scrotum and penis. Methods Clinical data, pathological data and follow-up of Paget＇s disease of the scrotum and penis were retrospective analyzed. Results The local amplified operation were performed in all of 13 cases. Wound surface of 10 cases were covered with residual skin of scrotum, while other 3 cases with free skin grafting. One case received three times of resections because relapses and then no relapse was happened after six-months follow-up. The other 12 cases didn＇t relapse after 2-64 months follow-up. Among 3 cases of inguinal lymph node enlargement, 1 case was carcinoma metastasis. No carcinoma metastasis was found in other cases. Conclusion The diagnosis of Paget＇s disease of the scrotum and penis depends mainly on pathological examination. Local amplified resection is crucial to cure. Cutaneous deficiency can be covered with scrotum skin flap or free skin grafting. Enlargement of inguinal lymph node was not always carcinoma metastasis. Insufficient range of resection, neoplastic cells infiltration into dermis and focal adenocarcinoma cells were major causes of relape.
出处
《中国男科学杂志》
CAS
CSCD
2005年第5期46-47,50,共3页
Chinese Journal of Andrology
