摘要
以歧化松香为原料,将其纯化得到脱氢松香酸,用硫酸二甲酯酯化后,通过12位溴代、7位氧化、13位硝化得到7-羰基-12-溴-13-硝基脱氢松香酸甲酯(Ⅴ),Ⅴ经过与叠氮化钠反应后,在甲苯中回流关环得到7-羰基-12,13-氧化呋咱脱氢松香酸甲酯(Ⅶ),Ⅶ再用三苯基膦脱氧得到7-羰基-12,13-呋咱脱氢松香酸甲酯Ⅷ,这两种产物的产率分别为83%和76%;产物经IR、1HNMR1、3CNMR和MS进行了表征。
Disproportionated rosin was purified to get dehydroabietic acid, which by esterification with （Me）2SO4 gave methyl dehydroabietate （ Ⅱ ）. Then Ⅱ was bromated at 12-position, oxidated at 7- position and nitrated at 13-position to give methyl 7-carbonyl-12-bromo-13-nitrodehydroabietate （ V ）. After treating V with sodium azide, methyl 7-carbonyl-12, 13-oxifurazandehydroabietate （ Ⅶ ） was obtained by refluxing in toluene. Ⅶ was further converted to methyl 7-carbonyl-12, 13- furazandehydroabietate （ Ⅷ ） through reacting with triphenyl phosphine. The compounds were characterized by IR, ^1 HNMR, ^13CNMR and MS.
出处
《精细化工》
EI
CAS
CSCD
北大核心
2005年第9期709-711,共3页
Fine Chemicals
基金
国家自然科学基金(20362002)
广西高校百名中青年学科带头人资助计划
广西青年科学基金(0229023)资助项目~~
