摘要
本文对电针足三里穴抗“束缚－冷冻”应激性胃溃疡大鼠一氧化氮（ＮＯ）、多巴胺（ＤＡ）和去甲肾上腺素（ＮＥ）的含量进行了分析，结果如下：①应激性胃溃疡大鼠血清ＮＯ含量比对照组非常显著下降， Ｐ＜０． ０１，胃窦粘膜ＤＡ含量显著下降， Ｐ＜０． ０５，胃体粘膜ＤＡ呈增高趋势；②电针足三里穴引起应激性胃溃疡大鼠ＮＯ水平回回升，与应激组相比， Ｐ＜０．０１。电针引起胃窦和胃体粘膜ＤＡ、ＮＥ含量改变，有双向调节作用。即原降低者上升、原升高者下降，分别与应激组相比，均为Ｐ＜０． ０１。提示电针对胃粘膜的保护作用是通过对ＤＡ和 ＮＥ的双向调节，发挥了ＤＡ的调控作用，影响ＮＥ的水平，通过ＮＯ的舒血管作用，调节血流量，增强粘膜防御能力而实现的。
This article was analysed contents of NO,DA and NE in stress gastric ulcer rats by restraint-cold on electro-acupuncture Zusanli point. The results were as follws, ①The NO contents in serum of stress gastric ulcer were very obviously decreases,compared with control group, P< 0.01; DA contents in gastric antral mucosa were markedly deceased,P<0. 05; DA in corpora ventriculi mucosa show a tendency to increase. ②Electro-acupuncture Zusanli point made NO level of the stress gastric ulcer rats recover,compared with stredd group, P<0. 01. Electro-acupuncture made DA and NE contents in antrum and corpora ventriculi mucosa change, had double-direction regulation. i. e. content of that which was decreased formerly rose, which was increased formerly fell,respectively compared with stress group,were all P<0. 01. It's suggested that protection of electro-acupuncture for gastric mucosa was put into effects by that,the double-direction regulation of acupuncture on DA and NE, regulation of DA, alteration of NE levels, the vascular relaxation participated by NO, then regulate gastric mucosal blood flow. strengthen defe-nsive of gastric mucosa.
基金
国家攀登计划资助!(经络研究JL-93012)
关键词
针灸疗法
一氧化氮
电针
足三里穴
胃溃疡
Nitric oxide Doamine Norepinephrine electro-acupuncture Zusanli point Stress gastric ulcer
