摘要
目的测定甲亢患者和正常对照个体的血浆B型脑钠肽(BNP)水平,评估BNP在甲亢性心脏病患者中的变化.方法将53例甲亢伴不同程度甲亢性心脏病患者分为3组,运用Triage诊断仪测定其治疗前后的血浆BNP水平,比较甲亢患者和正常人的血浆BNP水平.结果(1)甲亢性心脏病心功能NYHAⅡ级组和NYHAⅢ～Ⅳ级组患者的治疗前血浆BNP水平均显著高于正常对照组(均P＜0.01).(2)甲亢性心脏病心功能NYHAⅡ级组和NYHAⅢ～Ⅳ级组患者经治疗病情好转后的血浆BNP水平显著低于治疗前(P＜0.01).结论血浆BNP水平对于甲亢性心脏病患者心功能不全的诊断及疗效评价具有重要的价值.
Objective To evaluate the levels of plasma BNP in patients with hyperthyroid heart disease and the control subjects. Methods Fifty three hyperthyroidism patients were assigned to 3 groups according to their cardiac function. The levels of plasma BNP were measured by Triage diagnostic instrument before and after a two-week treatment in all hyperthyroidism patients and the results were compared to the control subjects. Results （1） The levels of plasma BNP in hyperthyroidism patients with cardiac functions of grades Ⅱ and Ⅲ - Ⅳ before treatment were significantly higher than that in the control subjects（P 〈 0.01）. （2） The levels of plasma BNP were significantly lower when the patients condition improved after a two-week treatment in hyperthyroidism patients with cardiac functions of grades Ⅱ and Ⅲ - Ⅳ. Conclusion BNP plays an important role in diagnosis of cardiac dysfunction in patients with hyperthyroid heart disease.
出处
《苏州大学学报（医学版）》
CAS
北大核心
2005年第4期630-632,共3页
Suzhou University Journal of Medical Science
关键词
B型脑钠肽
甲亢性心脏病
心功能不全
brain natriuretic peptide （BNP）
hyperthyroid heart disease
cardiac dysfunction
