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嗜线虫致病杆菌代谢产物CB6-1的分离、纯化与结构鉴定 被引量:9

Isolation and structural identification of main component CB6-1 produced by Xenorhabdus nematophilus var.pekingensis
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摘要 目的从对植物疫病有拮抗作用的嗜线虫致病杆菌北京变种(X enorhabdus nem a toph ilus var.p ek ing ensis)CB 6菌株的发酵产物中分离纯化抗菌组分,并鉴定其结构。方法采用多种层析方法对其进行分离,并采用UV、IR、M S和NM R对其进行结构鉴定。结果分离到一个主要组分CB 6-1,并鉴定其结构为3,4-二氢-8-羟基苯并吡喃衍生物。结论主要抗菌组分CB 6-1与文献报道的X encoum ac in 1相同。 Objective To isolate and purify the active components from fermentation broth of Xenorhabdus nernatophilus var. pekingensis CB6 and identify their structures. Method The active components were isolated by macroporous resin column chromatography and other extraction process. The structure of main component was identified by UV, IR, MS and NMR spectra. Results The main component, CB6-1 was isolated and identified as a 3, 4 dihydro-8-hydroxy-1H-2-benzopyran-l-one (isocoumarin) derivative. Conclusion The main component, CB6-1 was designated as Xenocournacin 1.
出处 《中国抗生素杂志》 CAS CSCD 北大核心 2005年第9期513-515,共3页 Chinese Journal of Antibiotics
基金 国家"863"计划基金资助项目(编号:AA2003241130)
关键词 嗜线虫致病杆菌 抗菌组分 分离 结构鉴定 CB6—1 Xenocoumacin 1 Xenorhabdus nematophilus Active components Isolation Structural identification CB6-1 Xenocoumacin 1
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