摘要
【目的】运用彩色多普勒血流显像(CDFI)检测各级肾动脉血流参数,探讨其在移植肾排异中的诊断价值与临床意义。【方法】对60例移植肾患者进行193次彩色多普勒血流显像(CDFI)检测,观察肾脏大小、实质厚度,二维图像,肾内血流灌注及动脉血流参数的变化,并与40例正常对照组对比。【结果】无排异组(84人次):肾大小与正常对照组无差异(P>0.05),二维图像与正常人相似。CDFI显示各级血管血流充填良好,呈血管树状,肾动脉血流(RBF)与正常对照组按近(P>0.05)。急性排异组(38人次):肾明显增大,实质增厚,锥体扩张,CDFI显示肾皮质边缘血管减少,肾动脉血流速度收缩期下降不明显,舒张期明显下降;搏动指数(PI),阻力指数(RI)明显增高,与正常人组比较相差显著(P<0.01)。慢性排异组(71人次):肾增大不明显,实质稍厚,回声增多,CDFI肾内血流显示不满意,肾动脉血流速度收缩期、舒张期均有不同程度下降,PI、RI增高,与正常对照组比较相差显著(P<0.01)。【结论】CDFI对移植肾排异反应的诊断及分型鉴别具有重要意义。
[Objective]To investigate the role of Color Doppler Flow Imaging （CDFI） of renal blood flow parameters in the diagnosis and clinical evaluation of renal transplant rejection, [Methods]Sixty renal transplant cases were tested 193 times and 40 healthy subjects were studied by CDFI. Items observed implied renal size,thickness of renal cortex in 2-D images. Renal artery （RA） and renal blood flow （RBF） were observed in CDFI. [Results]No rejection group（84 cases）： The 2-D images were similar to those of the normal group. Their transplanted kidneys were rich in blood. RBF appeared with full of branches. The renal size and RBF were the same as the normal group （ P〉0.05）. In the acute rejection group（38 cases） ： Kidneys became obviously larger. The renal cortex became thicker and the renal pyramide （py） dilated. Marginal blood vessels in renal cortex were lesser. The blood velocity was decreased only at the diastolic phase. Pulsation index （PI） and resistance index （RI） were higher than those of the normal （ P〈0.01）. In the chronic rejection group （71 cases）： Kidneys revealed no enlargement, the renal cortex thickened a little with hyperechoic appearance. RBFS were not perfused sufficiently. Blood velocities decreased both at systole and diastole at different degrees. PI and RI were sufficiently different to the normal （ P〈0.01 ）. [Conclusion]CDFI is valuable for rejection diagnosis and classification of transplanted kidneys.
出处
《医学临床研究》
CAS
2005年第9期1276-1279,共4页
Journal of Clinical Research
关键词
肾移植
移植物排斥
超声检查
多普勒
彩色
kidney transplantation
graft rejection
ultrasonography,doppler,color
