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HLA与小儿肾病综合征相关性的研究现状与进展 被引量:4

The Development of HLA Associates with Idiopathic Nephrotic Syndrome in Children
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摘要 小儿特发性肾病综合征(INS)同其它免疫性疾病一样,在其发生过程中有免疫遗传因素的参与和影响。人类白细胞抗原(HLA)-I,-II分子及其产物在INS的发病、临床过程、激素疗效、对细胞毒药物的敏感性、疾病复发、预后判断中有着重要作用。不同人种的研究表明,HLA与INS的相关性主要集中在A、B、DR、DQ位点,尤其是II类基因及一些单元型。INS的易感基因与HLA紧密连锁,HLA抗原不直接致病。
作者 兰涛 王桂琴
出处 《国外医学(儿科学分册)》 2005年第5期270-272,共3页 Foreign Medical Sciences(Section of Pediatrics)
基金 山西省攻关项目基金(051097-1)
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参考文献16

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