期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

缓激肽与心血管疾病 被引量：4

Bradykinin and Cardiovascular Disease
暂未订购
导出
摘要 详尽论述缓激肽在扩张血管、调节血压、减轻缺血再灌注损伤、抗心肌缺血中的作用及作用机制,并阐述高血压病、心肌梗死、心力衰竭中缓激肽对心脏的保护作用。 To expound the action mechanism of bradykinin in dilating vessels,regulating blood pressure,decreasing ischemic reperfusion injuries and anti-myocardial ischemia. It is reviewed in this article that bradykinin show a protective effect on myocardium in hypertension,myocardial infarction and heart failure.
作者 官玉红 李仁立
机构地区 华中科技大学同济医学院附属同济医院综合科
出处 《心血管病学进展》 CAS 2005年第B08期39-42,共4页 Advances in Cardiovascular Diseases
关键词 缓激肽 高血压病 心力衰竭 心肌缺血 心脏 Bradykinin Hypertension Heart failure Myocardial ischemia Heart
分类号 R54 [医药卫生—心血管疾病]
  • 相关文献

参考文献34

  • 1Heud O,Ramirez-Molina C Marshall P,et al. Investigation of bradykinin metabolism in human and rat plasma in the presence of the dual ACE/NEP inhibitors GW660511X and omapatrilat[ J] .J Pept Sci,2002,8( 11 ) :591-600.
  • 2Medeiros R, Cabrini DA, Ferreira J, et al. Bradykinin B1 receptor expression induced by tissue damage in the rat portal vein:a critical role for mitogen-activated protein kinase and nuclear factor-kappaB signaling pathways [ J ]. Circ Res,2004,94(10) : 1375-1382.
  • 3Ferreira J,Campos MM,Pesquero JB,et al. Evidence for the participation of kinins in Freund's adjuvant-induced inflammatory and nociceptive responses in kinin B1 and B2 receptor knockout mice[J]. Neuropharmacology,2001 ,41 (8) :1006-1012.
  • 4Gabra BH,Sirois P. Kinin B1 receptor antagonists inhibit diabetes-induced hyperalgesia in mice[ J] Neuropeptides,2003 37 ( 1 ) :36-44.
  • 5Stewen P, Outi S,Tuulikki N, et al. Cyclic AMP increases bradykinin receptor binding affinity in human endothelial cells [ J ]. Life Sci, 2004, 74 ( 23 ) : 2839-2852.
  • 6Sharma JN, A1-Dhalmawi GS. Role of bradykinin B( 1 ) receptors in diabetes-induced hyperalgesia in streptozotocin-treated mice[ J ]. Eur J Pharmacol,2002,57(2-3) :115-124.
  • 7Banik RK, Kozaki Y, Sato J, et al. B2 receptor-mediated enhanced bradykinin sensitivity of rat cutaneous C-fiber nociceptors during persistent inflammation[ J]. J Neurophysiol,2001,86( 6 ) :2727-2735.
  • 8Venema RC. Post-translational mechanisms of endothelial nitric oxide synthase regulation by bradykinin [ J ]. Int Immunopharmacol, 2002,2 ( 13-14 ) : 1755-1762.
  • 9Thuringer D, Maulon L, Frelin C. Rapid transactivation of the vascular endothelial growth factor receptor KDR/FIk-1 by the bradykinin B2 receptor contributes to endothelial nitric oxide synthase activation in cardiac capillary endothelial cells[ J]. J Biol Chem ,2002,277( 3 ) :2028-2032.
  • 10Batenburg WW ,Popp R, Fleming 1, et al. Bradykinin-induced relaxation of coronary m croarteries: S-nitrosothiols as EDHF [ J ]. Br J Pharmacol, 2004,142( 1 ) :125-135.

二级参考文献7

  • 1Muraki M,Tohda Y,Sugihara R,et al.The effect of TYB-2285 on dual phase bronchoconstr aiction and airway hypersensitivity in guinea-pigs actively sensitized with ovalbumin.J Pharm Pharmacol,1994,46: 883-886.
  • 2Liu Q,Fujimura M,Tachibana H,et al.Characterization of increased cough sensitivity after antigen challenge in guinea pigs.Clin Exp Allergy,2001,31: 474-484.
  • 3Pennock BE,Cox CP,Rogers RM,et al.A noninvasive technique for measurement of changes in specific airway resistance.J Appl Physiol,1979,46: 399-406.
  • 4Xiang A,Uchida Y,Nomura A,et al.Effects of airway inflammation on cough response in the guinea pigs.J Appl Physiol,1998,85:1847-1854.
  • 5Burch RM,Kyle DJ.Recent developments in the understanding of bradykinin receptors.Life Sci,1992,50:829-838.
  • 6Fox AJ,Umesh GL,Belvisi MG,et al.Bradykinin-evoked sensitization of airway sensory nerves: a mechanism for ACE-inhibitor cough.Nature Medicine,1996,7: 814-817.
  • 7Schuligoi R,Peskar BA,Donnerer J,et al.Bradykinin-evoked sensitization of neuropeptide release from afferent neurons in the guinea-pig lung.Br J Pharmacol,1998,125: 388-392.

共引文献18

同被引文献68

引证文献4

二级引证文献12

心血管病学进展
2005年 第B08期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部