老年高血压患者血尿酸水平与颈动脉硬化关系的临床研究被引量：16

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摘要目的探讨老年高血压患者血尿酸(UA)水平与颈总动脉平均内膜-中层厚度(IMT)的相关性。方法测定96例老年高血压患者颈总动脉IMT,血尿酸和空腹血糖(FBG),甘油三脂(TG)。按颈总动脉IMT将患者分为IMT正常组、IMT增厚组和斑块形成组。比较各组间UA水平,对颈总动脉IMT异常患者采用多元回归分析。分析颈总动脉IMT和血UA、空腹血糖和TG的关系。结果IMT正常组、IMT增厚组和斑块形成组血UA含量依次为:(286±50)、(345±47)和(429±51)mmol/L。三组间比较差异有显著意义(P<0.01)。动脉粥样硬化组中颈总动脉IMT和血UA、TG呈正相关关系(r=0.6321,P<0.01)。结论老年高血压患者颈总动脉IMT与血UA水平呈正相关,提示血UA水平可作为协助诊断早期动脉粥样硬化的指标。

作者张国成王静

机构地区吉林大学第一临床医院干部病房

出处《中国老年学杂志》 CAS CSCD 北大核心 2005年第9期1047-1048,共2页 Chinese Journal of Gerontology

关键词高血压颈总动脉血尿酸血管内膜

分类号 R544.1 [医药卫生—心血管疾病]

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参考文献9

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