摘要
目的:研究脑卒中后工作记忆损害的特点。方法:于2003年4月-2003年12月对118例脑卒中患者(观察组)和118例未患脑部疾病者(对照组),采用韦氏记忆量表(Wechsler Memory Scale,WMS)、威斯康星卡片分类试验(Wisconsin Card Sorting Test,WSCT)、连线测验A 和B(Trail Making Test A and B)进行了对比检测等。结果:两组比较,除语言记忆和数字顺背以外,其他差异均具有统计学显著性(P 对比<0.05)。连线测验B、连线测验A、分类错误差异较大,((?)±SE 观察组和对照组分别为200.0±15.2、133.3±7.19; 76.3±10.4、24.2±1.6;23.9±0.9、9.9±0.5)。不同卒中部位与对照组比较揭示:①额叶和顶叶卒中组WSCT 分类正确和错误差异有显著性,额叶的逆背,顶叶的语言记忆和视觉再认两组问差异有显著性(P<0.05)。②基底节卒中组,除顺背和语言记忆外差异均具有统计学意义(P<0.05)。③丘脑卒中组,WSCT 分类正确和错误、背数、视觉再认、视觉再生、连线测验A 和B 差异有显著性(P<0.05)。④顶叶-基底节联合卒中组,WSCT 分类正确和错误、语言记忆、视觉再认、视觉再生、连线测验A 和B 差异有显著性(P<0.05);脑卒中病人左右侧病灶的语言记忆和视觉再认差异有显著性(P<0.05)。语言记忆和视觉再认均数右侧较大((?)±SE 左侧分别为5.2±2.4、4.7±2.4;右侧分别为11.0±3.9、9.2±3.8)。结论:脑卒中组与对照组比较,执行功能、注意机能均出现显著异常。脑特定解剖部位的卒中有相应内容的工作记忆损害。右侧病灶组,空间记忆障碍和语言记忆障碍损害更明显。
Objectives： To study working memory deficit after stroke. Methods： 118 patients with stroke diagnosed by CT scans （ study group ） and 118 healthy people （ control group ） were collected from April to December in 2003. All objects were evaluated with Wechsler Memory Scale （WMS）, Trail Making Test A and B, and Wisconsin Card Test （WSCT）. Results： There were significant difference between the study group and control group in executive function, attention function, visual recognition and visual recall; The study group had more error in Trail making Test B, A and executive error（ x^- ± SE was 200.0± 15.2, 76.3± 10.4, 23.9± 0.9 ） than control group （133.3± 7.2, 24.2± 1.6, 9.9± 0.5）. Compared with control, patients with stroke of different locations had different deficits in working memory： Ofor frontal stroke, the deficit manifested in executive function, digital span （P〈0.05）. ②for parietal stroke, the deficit manifested in executive function, language memory, visual recognition. ③ for basal ganglia stroke, the deficit was diffusive except for digital span and language memory （P〉0.05）.④ for thalamic stroke, the deficit manifested in executive function, digital span, visual recognition and visual recall, （P〈0.05）. ⑤ for parietal and basal ganglia stroke, there were deficit in executive function, language memory, visual recognition, visual recall （P〈0.05）. Patients with left side strokes and right side strokes had significant differences in language memory and visual recognition （P〈0.05）. （ x^-± SE was 5.2± 2.4,4.7± 2.4 in left; 11.0± 3.9,9.2± 3.8 in right ） o Conclusion： Stroke patients have deficits in executive function, attention function. Location of the lesion is associated with types of deficit of working memory. There are more significant impairments in language and spatial memory after right side local lesion than left.
出处
《中国心理卫生杂志》
CSSCI
CSCD
北大核心
2005年第8期549-552,共4页
Chinese Mental Health Journal
关键词
卒中
病例对照研究
认知损害
记忆
stroke
case-control study
working memory
cognitive impairment
