摘要
目的研究急性胰腺炎患者血清ICAM-1、TNF-α和P选择素浓度和疾病严重程度的关系。方法选择重症急性胰腺炎(SAP)10例,轻症急性胰腺炎(MAP)10例,健康对照组10例,分别在患者入院后第1、3、5天抽取血清,检测血清中TNF-α、ICAM-1、P选择素水平。结果SAP患者第1天ICAM-1, TNF-α,P选择素血清水平与MAP患者及对照组之间无显著性差异,而第3、5天SAP患者ICAM-1,TNF- α,P选择素血清水平与MAP患者及对照组之间均有显著性差异(P<0.05)。结论ICAM-1、TNF-α、P 选择素浓度升高与急性胰腺炎的严重程度有关。
Objective To study the relation between the serum levels of ICAM-1, TNF-α, P selectin and pancreatic injury degree in patients with acute pancreatitis. Methods 10 patients with severe acute pancreatitis and 10 patients with mild acute pancreatitis were evaluated. 10 controls were obtained from healthy volunteers. Levels of ICAM-1 ,TNF-α and P-selectin were determined at day 1, 3 and 5 of admission. Results There was no significant difference in ICAM-1, TNF-α, P-selectin levels between SAP and MAP and control groups at day 1, but the difference was significant at day 3 and 5. Conclusions ICAM-1,TNF-α and P-selectin were closely related with pancreatic injury degree in acute pancreatitis.
出处
《胰腺病学》
2005年第3期170-171,共2页
Chinese JOurnal of Pancreatology
