摘要
目的探讨新型内冷微波天线作用于离体猪肝组织,凝固灶短轴径(SD)与凝固时间和功率的关系.方法采用MTC-3型微波治疗仪和新型水循环内冷微波天线,分别以不同时间和功率组合凝固新鲜离体猪肝组织,分别分析SD与时间和功率的关系.结果①功率一定时,在一定的时间范围(18 min)内, SD与作用时间有着高度的线性相关(r值 0.94～0.98,P＜0.01);功率30 W时,18 min后这种相关性将变差,因达一定时间点后,随着时间的延长,SD增加缓慢,甚至不再增加;但加大功率后该时间点后移;②时间一定时,功率与SD大小也存在高度近似的线性相关(r值 0.94～0.98,P＜0.01);③在18 min时间段内,SD可通过其与时间和功率的二元线性回归方程(P＜0.01)求出近似值.结论①在达一定时间点后,单纯延长作用时间,SD可能不再增大,但增加功率,延长凝固时间能够继续增大SD;②在一定时间范围内,植入式微波天线对离体肝组织SD大小与作用时间、功率存在高度近似的线性相关,这种关系将有助于指导临床应用.
Objective To probe the correlation between the short-axis diameter（SD） of microwave coagulation and the time（T） and/or power（P） using a new type of internally cooled microwave antenna. Methods A MTC-3 microwave apparatus with a new type of internally-cooled microwave antenna was used to coagulate a fresh porcine liver in vitro. The correlation was analyzed between the SD of coagulation necrosis and the time and/or power. Results ① Under the same power, there was high linear relationship （r = 0.94 - 0.98, P 〈0.01） between the SD of coagulation necrosis and the time. Beyond 18 minutes, the relation would become weak. With time increasing, the SD increased slowly, and consequently did not increase. After stopping increase, however, the time point would be prolonged if the power was amplified. ②The SD of coagulation necrosis and the power also had high linear relationship（ r = 0.94 - 0.98, P 〈0.01） at the definite time.③ Within 18 minutes, the regression equation of SD to the time and the power was SD= 10. 714 ＋ 1. 441T ＋ 0. 191P （ P 〈0.01）. Conclusions①After a certain period of time, the SD of coagulation necrosis would not increase with time; If the power was increased, however, the SD would increase with time. ②Within a definite period of time, there might be a high linear relationship between the SD of coagulation necrosis, the time and the power. The above findings are helpful to clinical therapy of liver tumor.
出处
《中华超声影像学杂志》
CSCD
2005年第9期706-708,共3页
Chinese Journal of Ultrasonography
