摘要
对一些食用油脂中的主要脂肪酸组份的量子化学参数进行计算,并与饲喂大鼠的相应生物学效应进行相关分析的结果表明,在各项大鼠血脂生化指标中,只有血清总胆固醇(TC)和低密度脂蛋白-胆固醇含量与脂肪酸各项量子化学参数间存在显著性相关(P<0.05),其中单不饱和脂肪酸(MUFA)的效果优于多不饱和脂肪酸(PUFA)。MUFA还可有效降低机体丙二醛含量,增强生物膜的流动性(P<0.01).不饱和脂肪酸分子中烯键碳原子上量子化学参数的急剧变化是油脂产生显著生物学效应的基本条件.
Quantum chemistry of main fatty acids in food oils was calculated, and the effectson rat lipid level, superoxide dismutase activity, platelet aggregation and biomembranefluidity were studied. The results were shown that, serum TC, LDL - C correlatedsignifieantly with quantum chemistry parameters (P<0.05), the bioeffects ofmonounsaturated fatty acids (MUFA) (P < 0. 01) were better than that ofpolyunsaturated fatty acids (PUFA) (P<0.05).MUFA effectively lowed ratmalondialdehyde content, enhanced biomembrane fluidity (P<0. 01). The sharp changeof quantum chmistry parameters in unsaturated fatty acids might be the basicrequirement for fat to induce significant bioeffects.
出处
《广州化学》
CAS
1996年第1期1-7,共7页
Guangzhou Chemistry
关键词
生物膜流动性
量子化学参数
脂肪酸
食用油
food oil, quantum chemistry, serum lipids, platelet function, biomembrane fluidity