1Anthes JC, Richard C, West RE, et al. Functional characterization of desloratadine and other antihistamines in a Chinese Hamster Ovary (CHO) cell line that expresses the cloned human bronchial smooth muscle cells ( HBSMC ). J Allergy Clin Immunol, 2000,104 (1Pt2):S385.
2Kreutner W, Hey JA, Anthes J, et al. Preclinical pharmacology of desloratadine, a selective and nonsedating histamine HI receptor antagonist. 1st communication: receptor selectivity, antihistaminic activity, and antiallergenic effects. Arzneimittelforschung, 2000, 50(4) :345-352.
3Cardelus I, Anton F, Beleta J, et al. Anticholinergic effects of desloratadine, the major metabolite of loratadine, in rabbit and guinea-pig iris smooth muscle. Eur J Pharmacol, 1999, 374(2) :249-254.
4Bayram H, Devalia JL, Khair OA,et al. Effect of loratadine on nitrogen dioxide-induced changes in electrical resistance and release of inflammatory mediators from cultured human bronchial epithelial cells. J Allergy Clin Immunol, 1999, 104(1) :93-99.
5Kleine-Tebbe J, Josties C, Frank G, et al. Inhibition of IgE- and nonIgE-mediated histamine release from human basophil leukocytes in vitro by a histamine H1-antagonist, desethoxycarbonyl-loratadine. J Allergy Clin Immunol, 1994, 93(2) :494-500.
6Kreutner W, Hey JA, Chiu P, et al. Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 2nd communication: lack of central nervous system and cardiovascular effects. Arzneimittelforschung, 2000, 50 (5) :441-448.
7Banfield C, Padhi D, Glue P, et al. Electrocardiographic effects of multiple high doses of desloratadine. J Allergy Clin Immunol, 2000,104(1 Pt2) :S383.
8Hey J, Anthes J, Barnett A, et al. Preclinical cardiovascular and CNS safety profile of desloratadine, a selective and nonsedating histamine H1-receptor antagonist. J Allergy Clin Immunol,2000,104(1Pt2):S383.
9Vuurman E, Ramaekers JG, Rikken G, et al. Desloratadine does not impair actual driving performance: a 3-way crossover comparison with diphenhydramin and placbo . Allergy, 2000,55 ( Suppl 63 ): 263 -264.
10Herron JM,Padhi D,Affrime MB, et al. Dose-proportionality, linearity, and pharmackinetics of desloratadine in health y adults. J Allergy Clin Immunol, 2000,104 (1 Pt 2) :S385.