摘要
目的探讨我院常见革兰阴性杆菌对头孢他啶(ceftazidime , CAZ)的耐药现状,为临床遏制细菌对头孢他啶耐药性提供帮助. 方法分析我院2001年1月～2004年6月住院患者标本中,分离出的2 779株病原菌对CAZ的药敏试验结果. 结果铜绿假单胞菌、假单胞菌属、大肠埃希菌、肺炎克雷伯菌、阴沟肠杆菌和不动杆菌属主要革兰阴性杆菌,对CAZ的耐药率分别由2001年的3%、13%、14%、14%、28%、11%上升到2004年的13%、36%、16%、22%、53%、57%. 结论常见革兰阴性杆菌对CAZ的耐药率有逐渐上升的趋势,要严格限制该药的不合理应用.
OBJECTIVE To survey drug resistance to ceftazidime（CAZ） in common Gram-negative bacilli in our hospital and thereby to bring the situation under control. METHODS A total of 2 779 strains of pathogenic bacteria were isolated from patients from Jan 2001 to Jun 2004, and drug resistance of these strains to CAZ was examined. RESULTS Resistance of Pseudornonas aeruginosa, Pseudornonas spp, Escherichia coli, Klebsiella pneurnoniae, Enterobacter cloacae and Acinetobacter spp to CAZ was found to be tend increasing from 3%, 13%, 14%, 14%, 28% and 11% in 2001 to 13%, 36%, 16%, 22%, 53% and 57% in 2004, respectively. CONCLUSIONS Resistance ratio of common Gram-negative bacilli to CAZ is high and tend to increase further. CAZ abuse needs to be given appropriate attention.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2005年第9期1047-1048,共2页
Chinese Journal of Nosocomiology
关键词
革兰阴性杆菌
抗生素耐药
头孢他啶
Gram-negative bacilli
Antibiotic resistance
Ceftazidime
