摘要
One pyridine ring was introduced into the basic structure of stilbene in place of one of the benzene rings for the purpose of evaluating the activity change.Started from methoxyl substituted chloromethylpyridine,five new polyhydroxy-azastilbene-2-nitrogen derivatives（4a4e） with（E）-isomer were synthesized via（Arbusow） reaction,Wittig-Horner reaction and demethalytion in a yield of 30%34% as the main products.Their structures were characterized by IR,MS and 1H NMR.
One pyridine ring was introduced into the basic structure of stilbene in place of one of the benzene rings for the purpose of evaluating the activity change. Started from methoxyl substituted chloromethylpyridine, five new polyhydroxy-azastilbene-2-nitrogen derivatives （ 4a - 4e ） with （ E ）-isomer were synthesized via Arbusow reaction, Wittig-Horner reaction and demethalytion in a yield of 30% - 34% as the main products. Their structures were characterized by IR, MS and ^1H NMR.
出处
《应用化学》
CAS
CSCD
北大核心
2005年第9期1039-1041,共3页
Chinese Journal of Applied Chemistry
关键词
氮杂芪
氯甲基吡啶
合成
azastilbene, chloromethylpyridine, synthesis
