摘要
为了探讨脑血管畸形的病理分型、血管形态结构与出血的关系,用光镜及组织化学方法,在对82例脑血管畸形的临床病理学特性进行比较观察的基础上,提出一种新的组织学分类法。结果:将脑血管畸形分为4种病理类型,即动静脉畸形(AVM,包括以动脉为主型AVM,以静脉为主型AVM,混合型AVM3个亚型)、毛细血管扩张症、静脉畸形和多种血管畸形混合型4型。发现病理组织学类型与脑出血有一定的关系,说明该分型具有临床实用价值。结果显示,血管壁薄弱或微小动脉瘤形成,是脑血管畸形出血的病理组织学基础。
Inthisstudytoevaluatetherelationshipbetweenthepathologicalclassification,his-tologicalcharacteristicsofcerebralvascularmalformationandtheriskofhemorrhage.Usinglightmicroscopyandhistochemistry,basedonthecareful,comparativeobservationofclinicopathologicalfeaturesof82casesofcerebralvascalarmalformations,anewhistologicalclassificationwassuggest-ed.Cerebralvascularmalformationswereclassifiedintothefourpathologicaltypes,namelythearte-riovenousmalformations(includingthearterialpredominantsubtype,thevenouspredominantsub-typeandthemixedsubtype),thevenousmalformation,thecapilarytelangiectasisandthemixedvascularmalformation.Itwasfoundthattherewereessentialrelationshipsbetweenthepathologicalclassificationandthehemorrhageinthecerebralvascularmalformations.Theclassificationswereconsideredtobeofpracticalvalueforclinicalapplication.Theweaknessofvascularwalsorthefor-mationofaneurysmswouldbethebasicpathologicalchangetoenhancetheriskofhemorrhagefromcerebralvascularmalformations.
出处
《中华神经科杂志》
CAS
CSCD
1996年第1期38-41,共4页
Chinese Journal of Neurology