摘要
报道大黄对单纯疱疹病毒（ＨＳＶ）感染小白鼠的治疗作用。药物剂量为３．３，６．７和１１．３ｇ／（ｋｇ·ｄ）．疗程７天。结果显示大黄能提高病毒感染鼠的存活率，延长存活时间，加快脑、心、肝、神经节中病毒的清除，且与剂量有关，抗病毒效果优于无环鸟苷。证明大黄对ＨＳＶ感染有治疗作用。
The mice model of herpes simplex virus infection was used to demonstrate antiviral ac-tivity of Rhei. Rhei extract was given subcutaneously in dosages of 3. 3g/kg, 6. 7g/kg and 11.3g/kg dailyfor 7 days. The results showed that the survival rate was higher, the survival time was lengthened and theelimination of virus from the brain, heart, liver and ganglion was quickened. The antiviral activity of Rheiwas found tobe better than acyclovir.
出处
《中药新药与临床药理》
CAS
CSCD
1996年第1期19-23,共5页
Traditional Chinese Drug Research and Clinical Pharmacology
关键词
中药
大黄
药理学
疱疹病毒感染
中医药疗法
Radix et Rhizoma Rhei/pharmacology
herpes virus infection/therapy, TCM
