摘要
目的提高膀胱结石并发鳞癌的诊治水平。方法回顾分析28例膀胱结石并发膀胱鳞状细胞癌的临床资料,男19例,女9例。年龄26~68岁,平均33岁。膀胱结石病程2~18年,平均4.5年。24例行尿细胞学检查发现异形细胞19例。KUB示膀胱单发结石5例,多发结石23例,IVU提示膀胱占位性病变者11例,B超和CT示膀胱占位性病变者17例。行膀胱镜检查28例发现膀胱肿瘤21例,肿瘤大小1.2cm×1.5cm^2.2cm×5.0cm。21例行膀胱部分切除术,其中6例行输尿管膀胱移植术。7例行全膀胱切除术。结果病理报告均为膀胱鳞状细胞癌;G111例,G212例,G35例;T111例,T212例,T35例。22例获随访1~8年,平均3年,1年和5年生存率分别为63.6%(14/22)和16.7%(3/18)。结论膀胱结石并发膀胱鳞癌恶性程度高,早期诊断和手术治疗极其重要。
Objective To summarize the clinical experience in the diagnosis and treatment of cystolithiasis complicated by squamous cell carcinoma （SCC） of the bladder. Methods Retrospective analysis was performed in 28 patients （19 men and 9 women） with cystolithiasis complicated by SCC of the bladder. Their age ranged from 26 to 68 years with a mean of 33 years. The disease course of cystolithiasis ranged from 2 to 18 years with a mean of 4.5 years. Among the 24 cases who underwent urine cytology, atypical cells were found in 19 cases. KUB showed solitary stone of the bladder in 5 case and multiple stones in 23. Spaceoccupying lesions were noted in 11 cases on IVU, in 17 cases on B-ultrasonography and CT scan. Cystoscopy was performed in 28 cases, and tumors were found in 21 cases. The size of the tumors ranged from 1.2 cm×1.5 cm to 2.2 cm×5.0 cm. Partial cystectomy was performed in 21 cases, including ureterocysto-transplantation in 6 cases. Radical cystectomy was performed in 7 cases. Results Pathology revealed SCC of the bladder in all 28 cases, including G1 in 11 cases, G2 in 12 cases, G3 in 5 cases; T1 in 11 cases, T2 in 12 cases, T3 in 5 cases. Twenty-two patients were followed up for 1 to 8 years with a mean of 3 years. The 1-and 5-year survival rates were 63.6% （14/22） and 16.7% （3/18）, respectively. Conclusions Cystolithiasis is the main cause of SCC of the bladder. Early diagnosis and surgical treatment is very important for such patients.
出处
《中华泌尿外科杂志》
CAS
CSCD
北大核心
2005年第9期605-606,共2页
Chinese Journal of Urology
