摘要
综述亚洲b型流行性感冒(流感)嗜血杆菌(Hib)疾病和疫苗推广使用情况。流感嗜血杆菌是全世界儿童发病和死亡的主要原因之一,Hib常引起儿童严重感染。Hib结合疫苗的问世,大大减少了发达国家Hib疾病的发病率。尽管认识到Hib疾病的重要性,亚洲绝大多数国家仍未考虑使用这一疫苗,主要原因:亚洲国家Hib疾病负担不清楚和疫苗的价格。亚洲国家如何对待Hib疫苗问题:已知有高发病率的国家和地区应考虑使用;已经着手使用的国家应及时评价其免疫效果;疾病负担不清楚的国家与地区应与政府和专门机构积极合作,进一步开展相关研究。Hib疫苗使用应该提到决策机构的议事日程上来。
To review Haemophilus influenzae type B （Hib） diseases and Hib vaccine in Asia. Haemophilus influenzae is a leading cause of children＇ s infectious diseases （bacterial meningitis and pneumonia） and the mortality all over the world. Hib has been estimated to cause 〉90% children＇s severe infection. Although invasive Hib disease has been reduced substantially wherever Hib conjugate vaccines have been introduced into routine childhood immunization schedules and the importance of Hib disease has been realized, these vaccines have not been used by most of the countries in Asia because of the limited information of Hib disease burden available and the high price of these vaccines. Those countries whose morbidity is high should introduce the vaccines as soon as possible. Those countries which has introduced the vaccines should estimate the imunization effect in time. Those countries which Hib disease burden is uncertainty should carry on coorperate with the government and health policy makers actively. Every country should cooperate with the correlated research organizations. Hib vaccines should be introduced into routine childhood immunization schedules as soon as possible in Asia countries.
出处
《中国计划免疫》
2005年第4期327-330,共4页
Chinese Journal of Vaccines and Immunization
