摘要
目的:比较经单或双侧椎弓根将自固化磷酸钙骨水泥(autosetting calcium phosphate cement,ACPC)灌注入骨质疏松性压缩骨折椎体的成形效果。方法:自7具老年新鲜尸体脊柱上取T10￣T12或L1￣L3连续三节段椎体共10个标本,分别测定初始中间椎体和相邻椎间盘非破坏性载荷下标本前屈、后伸、侧屈和扭转运动时的应力、应变值和轴向刚度。然后在前屈压缩下造成中间椎体骨折。标本随机分成两组,分别经单侧和双侧椎弓根将3ml ACPC注入椎体后再同前测试,并测定中间椎体极限抗压强度和刚度。结果:成形术后中间椎体在非破坏性载荷下标本前屈、后伸和侧屈运动时应力和轴向刚度较初始无明显增加,经单侧和双侧椎弓根灌注组之间也无明显差异,但扭转刚度皆有下降。两组抗压极限强度较初始都有显著性提高。两组相邻椎间盘应力和轴向刚度皆无明显变化。结论:经单侧和双侧椎弓根灌注3ml ACPC都能较好恢复骨质疏松性压缩骨折椎体的生物力学性能,对相邻椎间盘的抗压力学性能影响小。
Objective：To compare the effect between unipedieular and bipedieular vertebroplasty assisted with autosetting calcium phosphate cement （ACPC）.Method：Ten specimens consisting of three continuous thoraeolumbar vertebrae were obtained from 7 fresh cadavers.Initial stress,strain and axial stiffness of middle vertebrae and adjacent intervertebral discs were determined respectively during flexion,extension,lateral bending and torsion under nondestructive load.After flexional compression fractures were experimentally created in the middle vertebrae,specimens were divided into two groups randomly.The middle vertebral bodies were then strengthened using either unipedicutar or bipedieular injections of 3ml ACPC respeetively.A forementioned values and utmost strength and stiffness of middle vertebrae were tested postoperatively.Result：Compared with the initial,postoperative stress and axial stiffness of middle vertebrae had no significant increase during flexion,extension or lateral bending ureter nondestructive load.And there were no significant difference between two groups.But torsion stiffness in both groups declined.Strength significantly increased in two groups while there were no marked difference between them.Stress and axial stiffness of adjacent intervertebral disc had no significant change in either group.Conclusion：Both unipedieular and bipedieular vertebroplasty assisted with ACPC can restore biomeehanieal property of compressed osteoporotic vertebrae while have little effect on adjacent intervertebral disc.
出处
《中国脊柱脊髓杂志》
CAS
CSCD
2005年第9期549-552,共4页
Chinese Journal of Spine and Spinal Cord
关键词
椎体成形术
磷酸钙
骨水泥
生物力学
脊柱骨折
Vertebroplasty
Calcium phosphate cement
Biomechanics
Spine fractures
