摘要
目的探讨肝胆管结石合并肝胆管癌的临床表现及诊治特点。方法回顾性分析54例肝胆管结石合并肝胆管癌的临床资料、诊断及治疗情况。结果结石伴发肝胆管癌的发生率为11.8%。由于缺乏特异性临床表现,该合并症术前诊断困难,术前能明确诊断者仅占11.1%。根治性切除率仅占51.8%,根治性切除者预后较未切除者为好(P≤0.05)。结论长期反复发作的肝胆管结石易合并胆管癌,该病早期诊断困难,疗效差,预后不良,因此,肝胆管结石,特别是反复发作的肝胆管结石应及早手术。对于术中确诊为肝胆管癌者,应争取行根治性切除,可能获得良好的预后。
Objective To investigate the clinical manifesfations and diagnostic and therapeutic features of cholangiocarcinoma associated with hepatolithiasis. Methods The clinical data, the diagnotic and therapeutic featares of 54 cases of cholangiocacinoma associated with hepatolithiasis were retrospectively analyzed. Results The occurrence rate of hepatolithiasis concomitant with hepatocholangiocarcinoma was 11.8% . Due to a lack of specific clinical manifestations, the preoperative diagnosis of this condition was difficult. In this series, the correct diagnotic rate of hepatocholangiocarcinoma before operation was only 11. 1%. The radical resection rate was 51. 8%. Radical resection of the tumor had a better prognosis than that of non-resection of tumor. Conclusions Patients with long-term recurrent hepatolithiasis tended to have associated cholangiocarcinoma. Early diagnosis of the disease was difficult, and the treatment results and prognosis were poor. Therefore, patients with hepatolithiasis, espesially those with recurrent attacks, should undergo operation early. In cases diagnosed as hepatic cholangioearcinoma at operation, a radical resection should be performed, if possible, and a favorable outcome may be attained.
出处
《中国普通外科杂志》
CAS
CSCD
2005年第8期567-569,共3页
China Journal of General Surgery
关键词
胆管肿瘤/外科学
胆管肿瘤/诊断
胆管
肝内
Bile Duct Neoplasms/surg
Bile Duct Neoplasms/diag
Bile Ducts, Intrahepatic
