摘要
目的研究软组织多形性脂肪瘤的临床病理学特点,探讨其诊断和鉴别诊断。方法对3例软组织多形性脂肪瘤进行HE染色和免疫组化观察,并复习文献。结果光镜下肿瘤由单核或多核巨细胞、成熟的脂肪组织及梭形细胞组成,多核巨细胞呈花冠样。肿瘤细胞CD34和S100(+)。结论多形性脂肪瘤是一种少见的良性肿瘤,手术切除,预后良好,应注意与其他良、恶性肿瘤相鉴别。
Objective To study the elinieopathologieal features of pleomorphie lipoma and to explore the diagnosis and differential diagnosis of it. Methods Three cases of pleomorphie lipoma were studied by H-E staining and immunohistochemistry. Results Microscopically, the neoplasm consisted of pleomorphie and multinueleated giant cells （floret cell） in a myxoid stroma containing mueopoiysaeeharides, along with an admixture of mature adipocytes, spindle cells. Immunohistoehemical analysis revealed that pleomorphie lipoma was positive for CD34 and S-100. Conclusion Pleomorhie lipoma is a rare benign, pseudosareomatous soft tissue neoplasm with favorable outcome. The diagnosis and differential diagnosis of pleomorphie lipoma are important.
出处
《诊断病理学杂志》
CSCD
2005年第4期257-259,i0004,共4页
Chinese Journal of Diagnostic Pathology
关键词
多形性脂肪瘤
组织形态
免疫组化
鉴别诊断
Pleomorphic lipoma
Histology
Immunohistochemistry
Differential diagnosis
