摘要
目的探讨垂体肉芽肿的临床特点与治疗。方法报道1例病人的临床资料,并复习文献19例。结果患者以头痛和视力障碍起病,头颅MRI提示鞍内占位性病灶,信号不均匀,视交叉明显受压上抬,手术发现病灶有出血,病理证实为垂体肉芽肿。文献19例垂体肉芽肿中,Rathke's囊肿破裂引起12例,胆固醇、浆细胞、巨细胞肉芽肿各1例,分支杆菌感染引起1例,原因不明3例;临床表现不典型,所有病例均行手术并靠病理确诊。结论垂体肉芽肿非常罕见,临床诊断困难,常经病理确诊。术后激素治疗,预后良好。
Objective To investigate the clinical characters and treatments of pituitary granuloma. Methods A patient of pituitary granuloma with bleeding was reported, and 19 cases in literatures were reviewed. Results The patient showed headache and visual disturbance, cranial MRI scan revealed a contrast enhancing intrasellar mass and signal asymmetry, vision cross was pressed and raised. Bleeding was found in the operation, and pituitary guanuloma was demonstrated by pathology. In the literature, there were 19 cases of pituitary granuloma, 12 cased were Rathke＇s cleft cyst, 3 cases were cholesterol granuloma, plasma cell granuloma and giant cell granuloma; 1 case was caused by the infection of branch bacilli; there were 3 cases with no significant causes. The clinical presentations of all these cases were not characteristic, and all the cases were diagnosed by pathology. Conclusion Pituitary granuloma is very rare in clinic, the diagnosis is difficult, pathology is always needed. These patients are best managed by histological confirmation of the lesion followed by adequate hormonal replacement.
出处
《重庆医学》
CAS
CSCD
2005年第9期1357-1358,1360,共3页
Chongqing medicine
关键词
垂体肉芽肿
诊断
治疗
pituitary granuloma
diagnosis
treatment
