摘要
本研究对89例肝外胆道梗阻的患者作利胆灵治疗及对照观察。结果表明,利胆灵可加速部分性胆道梗阻患者的黄疸消退及肝功能恢复。完全性胆道梗阻者服用利胆灵可加重肝功能损害。实验研究提示利胆灵可增加胆红素的排出,有增加肝血流量作用。
A total of 89 cases with extrahepatic jaundice Were studied Clinically.All patients were divided into two groups at random:control group and Li Dan Ling treatment group,It was found that:(1) liver functions in the patients with obstructive jaundice were injured severely;bilirubin,R_(15)ICG, m-GOT,and γ-GT were increased significantly;(2)in patients with imcomplete biliary obstruction or after the relief of obstruction,liver functions could be improved gradually.They were improved more quickly in patients of the Li Dan Ling treatment group;(3)for the patients suffering from complete biliary tract obstruction,until the obstruction was relieved liver function could not be improved.After the herbal medicine,all the indicators would be further worsened before the relief of the obstruction,and the value of'b'would be positive.The increase in m-GOT and γ-GT was higher than in the control group,indicating the liver functions were further injured.Therefore,the herbal cholegogue was not suitable for the patients before the obstruction was relieved. The further investigations showed that excretion of bilirubin from the bile could be accelerated by Li Dan Ling,and after herbal administration,the cholesterol level in bile was lowered significant- ly;the liver blood flow in normal and jaundiced rats would be increased 30 to 90 min.after administering the herbs.
出处
《中西医结合杂志》
CSCD
北大核心
1989年第3期137-140,131,共4页
