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甲硝唑凝胶的质量研究 被引量:7

Study on quality control standard of metronidazolc gel
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摘要 0.75%甲硝唑凝腔局部应用对脓疤型或丘疹型酒糟鼻治疗效果显著,且无任何不良反应。以含量测定、腔凝强度及pH值测定作为本制剂的质量控制指标。 any people are embarrased by the presence of rosacea,which is a chronic in flamatory disease. We have de-veloped a 0. 75% concentration gel of metronidazole according to the newest report. Metronidazole content in thegel was directly measured by UV spectrophotometry at 277nm, with few interference by other ingredients, includingthe base. The average recovery was 98. 7 % (RSD= 1. 76 %). This method is very simple. Convenient and sensitive.PH and gelatinous strength was measured,too.
出处 《中国医院药学杂志》 CAS CSCD 北大核心 1996年第1期24-25,共2页 Chinese Journal of Hospital Pharmacy
关键词 甲硝唑 凝胶 质量控制 medronidazole, gel,quality control
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