摘要
本文对26例视网膜静脉阻塞患者进行血小板聚集试验(P_(Ag)T)测定,并以30例健康者作对比观察。结果:患者组在以肾上腺素及 ADP 诱导剂的 P_(Ag)T 测定中,其血小板最大聚集率明显高于对照组 P<0.01～0.001),提示血小板聚集功能变化与视网膜静脉阻塞疾病密切相关。另外,初步探讨了中医药治疗对本病血小板聚集功能的影响,结果发现治疗后血小板最大聚集率较治前明显降低,从而提示中医药治疗能改善血小板聚集功能。
The authors studied the maximum platelet aggregation curve(PAgT max%)in 25 patients of retinal vien occlusion(RVO)before treatment with TCM and compared with 30 normal adults as controls.The results of PAgT max% induced by 1.0μg/ml adrenaline were 67.44±20.91 in 25 patients of RVO,and 54.30±12.66 in normal adults,when induced by 0.6μmol ADP there were 65. 68±11.25 and 45.37±14.57 respectively.It showed higher than normal value in 20 out of 25 patients of RVO.The results indicated that there was a significant correlation with the RVO and raising of PAgT max%(P<0.01～0.001),but there was no significant difference between male and female groups(P>0.05). After treatment with TCM,14 out of the 20 abnormal PAgT max% cases were examined,the results of PAgT max% induced by 1.0 μg/ml adrenaline reduced from 70.50±7.32 before treatment to 50.93±19.40 after treatment,and by 0.6 μgmol ADP reduced from 70.86±8.85 before treatment to 46.21±10.88 after treatment.The treatment with TCM seemed to convert the high PAgT max% to normal value and also improved the symptoms and signs.
