摘要
近年来研究发现黏附分子与动脉粥样硬化密切相关,参与了动脉粥样硬化的发生、发展过程,特别是循环血液中可溶性黏附分子的水平与疾病的活动程度和斑块的稳定性有关。抑制黏附分子及其介导的黏附作用可望成为治疗动脉粥样硬化的有效手段之一。
During recent years, adhesion molecules have been identified to be important in the pathogenesis of atherosclerosis. They play a crucial role in the development and progression of atherosclerotic lesion. Especially levels of soluble adhesion molecules in the circulation are associated with extent of disease and plaque instability. Anti-adhesion therapy may be a potential therapeutic strategy to combat atherogenesis.
出处
《心血管病学进展》
CAS
2005年第5期494-498,共5页
Advances in Cardiovascular Diseases
基金
国家自然科学基金资助项目(30271674)
关键词
黏附分子
动脉粥样硬化
炎症
可溶性形式
Adhesion molecules
Atherosclerosis
Inflammation
Soluble forms