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40例老年及老年前期慢性阻塞性肺疾病患者20年追踪 被引量:8

The prospect of prevention and treatment of Cor pulmonale on a 20-year follow-up of 40 middle to old aged cases of COPD and Cor pulmonale
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摘要 目的为了进一步了解老年及老年前期慢性阻塞性肺疾病(COPD)的发生发展规律,寻求防治方向。方法对40例老年及老年前期COPD及早期肺心病患者进行20年追踪观察。发现有23例占70%演变为肺心病或肺动脉高压,以致肺心病患者总例数由7例累计到30例,伴发其它老年病及肿瘤者亦增多。结果到20年末尚存活19例占48%,死亡21例占53%。其中肺心病组死亡19例占死亡总数的91%,死于呼吸衰竭及心肺功能衰竭者11例占52%。结论鉴于肺心病的死亡率高,抢救耗费巨大而不能根治。对肺心病的防治方向应转向防治COPD,预防肺心病的形成。而防治COPD的重点则在于戒烟、防治呼吸道感染、加强防寒、防感冒,适当的呼吸锻炼及进一步开展呼吸康复工作。 Objective To study the outcome of current therapy for COPD and Cor pulmonale by long-term follow-up of COPD patients. Method, Forty cases of middle to old aged COPD and Cot pulmonale patients were followed up for a period of 20 years. Results The pulmonary function of all the patients reduced significantly more than healthy elderly, while no difference was noted in blood gas analysis. 23 patients with advanced COPD developed cor pulmonale, so that the number of cases with cor pulmonale increased significantly from 7 to 30. By the end of follow-up 19 cases survived (48%), 21 cases (Cot pulmonate 19, COPD 2) died (53%). Conclusions In view of the high mortality of cor pulmonale and the tremendous treatment cost, it was considered that the prospect for cor pulmonale management should be put on treating COPD to avoid development of Cot pulmonale. The keys of treating COPD are stop of smoking, protection from cold, early treatment of respiratory infection and fur- ther establishment of pulmonary rehabilitation work.
机构地区 北京医院呼吸科
出处 《中华结核和呼吸杂志》 CAS CSCD 北大核心 1996年第1期29-32,共4页 Chinese Journal of Tuberculosis and Respiratory Diseases
关键词 老年人 慢性病 阻塞性肺疾病 Aged Lung diseases, obstructive Pulmonary heart disease
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