摘要
美国国立卫生院(NationalInstitutesofHealth,NIH)是当今世界上最著名的医学领域研究和管理机构。2003年9月该机构公布了未来10年能导致生命科学原创发现的重点研究领域和研究战略。重点研究领域包括:1.生物学通道和网络研究,重点是蛋白组学和代谢组学研究。2.建立分子库和分子图像及筛选中心,开展化学信息学研究和分子图像探针合成关键设备研制。3.结构生物学研究领域。4.生物信息学和计算生物学研究领域。5.纳米医学研究领域。研究战略之一是加强未来医学研究队伍建设,重点支持高风险研究,建立多学科交叉研究队伍和建立政府和私人机构的合作联系。研究战略之二是重铸临床研究,重点加快科学发现向临床应用转化的研究,加强临床工作人员的培训和建立临床研究网络。NIH确定的研究领域和研究战略对加速分子医学革命的到来有重要意义,对我国生命科学研究和宏观管理具有极大的参考价值。
National Institutes of Health （NIH） is one of the world＇s foremost medical research and management centers. It issued the roadmap and strategy for future 10-year＇s medical research on September 2003. The new pathways to discovery including： 1. Building blocks, biological pathways, and networks. Key point is Proteomics and Metabolomics. 2. Creation of NIH Bioactive Small Molecule Library, Image and Screening Centers, Key point is Cheminformatics and development of high specificity/high sensitivity probes to improve detection. 3. Structural Biology research field. 4. Bioinformatics and Computational Biology research areas. 5. Nancrmedicine research field. One of the research strategy is building research teams of the future, supporting high-risk research, interdisciplinary research and public-private partnerships. The other research strategy is reengineering the clinical research, including translational research, clinical work force training and building clinical research networks. Future molecular medicine will benefit from the roadmap , also the roadmap and strategy will be great helpful for medical research and management in our country.
出处
《世界科技研究与发展》
CSCD
2005年第3期93-98,共6页
World Sci-Tech R&D
