摘要
近年认为糖尿病是一种炎症性疾病。巨噬细胞是一种重要的炎症细胞,与糖尿病肾病的发生和进展有密切关系。调控巨噬细胞的浸润与活化可能是糖尿病肾病的防治新途径。
出处
《国外医学(泌尿系统分册)》
2005年第5期694-696,共3页
Foreign Medical Sciences(Urology and Nephrology Foreign Medical Sciences)
参考文献22
-
1Nathan C. Points of control in inflammation. Nature, 2002,420(6917):846 - 852.
-
2Tracey KJ.The inflammatory reflex. Nature,2002,420(6917):853-859.
-
3Barzilay JI, Abraham L, Heckbert SR, et al. The relation of markers of inflammation to the development of glucose disorders in the elderly:the Cardiovascular Health Study. Diabetes,2001,50(10) :2384 - 2389.
-
4Uesugi N, Sakata N, Horiuchi S, et al. Glycoxidation - modified macrophages and lipid peroxidation products are associated with the progression of human diabetic nephropathy. Am J Kidney Dis, 2001,38(5):1016 - 1025.
-
5Liu L, Wang Y, Fan Y, et al. IFN - gamma activates cAMP/PKA/CREB signaling pathway in murine peritoneal macrophages. J Interferon Cytokine Res,2004,24(6) :334- 342.
-
6Atkins RC, Holdsworth SR, Glasgow EF, et al. The macrophagen in human rapidly progressive glomerulonephritis. Lancet, 1976, 1 (7964):830 -832.
-
7van Goor H, van der Horst ML, Fidler V, et al. Glomerular macrophage modulation affects mesangial expansion in the rat after renal ablation. Lab Invest, 1992, 66(5) :564 - 571.
-
8Ikezumi Y, Hurst LA, Masaki T, et al. Adoptive transfer studies demonstrate that macrophages can induce proteinuria and mesangial cell proliferation. Kidney Int,2003,63(1):83-95.
-
9Saito T, Yusa A, Soma J, et al. Significance of leukocyte infiltration in membranous nephropathy with segmental glomerulosclerosis. Nephron,1998,80(4) :414 - 420.
-
10Diamond JR,Pesek- Diamond I. Sublethal X- irradiation during acute puromycin nephrosis prevents late renal injury: role of macrophages. Am J Physiol, 1991,260(6 Pt 2): F779 - 786.
二级参考文献23
-
1周同,孙桂芝,李晓,吴开胤,张冬青,陈玉英,胡庆沈,陈楠.黏附分子P-选择素与树突状细胞在人肾小管间质病变中的作用[J].上海第二医科大学学报,2004,24(7):501-504. 被引量:11
-
2周同,王锋,孙桂芝,张玉梅,张冬青,陈楠.抗P-选择素功能域单抗体外抗黏附作用的实验研究[J].上海第二医科大学学报,2004,24(7):514-517. 被引量:3
-
3[1]Yang N,Wu LL,Nikolic-Paterson DJ,et al.Local macrophage and myofibroblast proliferation in progressive renal injury in the rat remnant kidney [J].Nephrol Dial Transplant,1998,30:1 967-1 974.
-
4[2]Yamate J,Sato K,Ide,M,et al.Participation of different macrophage populations and myofibroblastic cells in chronically developed renal interstitial fibrosis after cisplatin-induced renal injury in rats [J].Vet Pathol,2002,39:322-333.
-
5[4]Pendl GG,Robert C,Steinert M,et al.Immature mouse dendritic cells enter inflamed tissue,a process that requires E- and P-selectin,but not P-selectin glycoprotein ligand 1 [J].Blood,2002,2(3):946-956.
-
6[10]Ruiz-Ortega M,Ruperez M,Lorenzo O,et al.Angiotensin Ⅱ regulates the synthesis of proinflammatory cytokines and chemokines in the kidney[J].Kidney Int,2002,82(Suppl.) :12 -22.
-
7[11]Nahmod KA,Vermeulen ME,Raiden S,et al.Control of dendritic cell differentiation by angiotensin Ⅱ[ J].FASEB J,2003,17:491-493.
-
8[12]Fakhouri F,Placier S,Ardaillou R,et al.Angiotensin Ⅱ activates collagen type Ⅰ gene in the renal cortex and aorta of transgenic mice through interaction with endothelin and TGF- [ J].J Am Soc Nephrol,2001,12:2 701 -2 710.
-
9[13]Dinh DT,Fraumant AG,Johnston CI,et al.Angiotensin receptors:distribution,signaling and function[ J ].Clin Sci,2001,100:481-487.
-
10[14]Muller DN,Shagdarsuren E,Park JK,et al.Immunosuppressive treatment protects against angiotensin Ⅱ-induced renal damage [J].Am J Pathol,2002,161:1 679-1 693.
共引文献8
-
1张玉梅,孙桂芝,周同.细胞黏附分子与肾脏疾病[J].上海第二医科大学学报,2004,24(7):524-527. 被引量:7
-
2周同,孙桂芝,李晓,吴开胤,张冬青,陈玉英,胡庆沈,陈楠.肾组织粘附分子及树突状细胞与IgA肾病小管间质病变的关系[J].肾脏病与透析肾移植杂志,2004,13(6):530-533. 被引量:4
-
3周同,孙桂芝,张玉梅,赵亚鹏,张雁云,张冬青,陈楠.抗炎调节物对人树突状细胞表型及致炎细胞因子分泌的影响[J].细胞生物学杂志,2006,28(1):89-94.
-
4周同,孙桂芝,张玉梅,赵亚鹏,吴开胤,张雁云,张冬青,陈楠.抗P-选择素凝集素-EGF功能域单抗对人树突状细胞成熟及功能抑制作用分析[J].细胞生物学杂志,2006,28(2):201-205. 被引量:1
-
5周同,孙桂芝,李晓,张玉梅,吴开胤,张雁云,张冬青,陈楠.树突状细胞在肾小管间质炎症病变中的作用及抗黏附干预调节的研究[J].中华肾脏病杂志,2006,22(10):605-611. 被引量:11
-
6周同,张雁云,孙桂芝,张玉梅,倪培华,陈永熙,吴开胤,张冬青,陈楠.人DC体外分化成熟特性及抗P-选择素功能域单抗对其干预调节[J].中国科学(C辑),2006,36(6):524-533. 被引量:2
-
7李晶,刘华林,蒋玉红,刘薇.血清P-选择素与儿童过敏性紫癜的相关性研究[J].中国中西医结合肾病杂志,2009,10(4):332-333. 被引量:2
-
8唐平,刘丹,杨川,刘珊英,李红辉,王碧飞.缬沙坦对早期糖尿病鼠肾脏巨噬细胞浸润的影响[J].中华全科医学,2010,8(2):136-137. 被引量:2
同被引文献25
-
1Lim AK, Tesch GH. Inflammation in diabetic nephropathy[J]. Mediators Inflamm, 2012, 2012 (2012): 146154. DOI: 10.1155/ 2012/146154.
-
2Liu J, Wang C, Liu F, et al. Metabonomics revealed xanthine oxidase-induced oxidative stress and inflammation in the pathogenesis of diabetic nephropathy[J]. Anal Bioanal Chem, 2015, 407(9): 2569-2579. DOI: 10.1007/s00216-015-8481-0.
-
3Landstr~m M. The TAK1- TRAF6 signalling pathway[J]. Int J Biochem Cell Biol, 2010, 42(5): 585- 589. DOI: 10.1016/j. biocel. 2009.12.023.
-
4Sakurai H. Targeting of TAK1 in inflammatory disorders and cancer[J]. Trends Pharmaeol Sei, 2012, 33(10): 522-530. DOI: 10.1 O16/j.tips.2012.06.007.
-
5Chow F, Ozols E, Nikolic- Paterson DJ, et al. Macrophages in mouse type 2 diabetic nephropathy: correlation with diabetic state and progressive renal injury[J]. Kidney Int, 2004, 65(1): 116-128.
-
6Ying W, Cheruku PS, Bazer FW, et al. Investigation of macrophage polarization using bone marrow derived macrophages[J]. J Vis Exp, 2013, (76). DOI: 10.3791/50323.
-
7Navarro JF, Mora-Femandez C. The role of TNF-a in diabetic nephropathy: pathogenic and therapeutic implications[J]. Cytokine Growth Factor Rev, 2006, 17(6): 441-450.
-
8Cheng CI, Chen PH, Lin YC, et al. High glucose activates Raw264.7 macrophages through RhoA kinase- mediated signaling pathway[J]. Cell Signal, 2015, 27(2): 283-292. DOI: 10.1016/j.cellsig.2014.11.012.
-
9Verhave JC, Bouchard J, Goupil R, et al. Clinical value of inflammatory urinary biomarkers in overt diabetic nephropathy:a prospective study[J]. Diabetes Res Clin Pratt, 2013, 101(3): 333-340. DOI: 10.1016/j.diabres.2013.07.006.
-
10Camilla R, Braehemi S, Pichette V, et al. Urinary monoeyte chemotactic protein 1: marker of renal function decline in diabetic and nondiabetie proteinuric renal disease[J]. J Nephrol, 2011, 24(1): 60-67.
二级引证文献3
-
1卫洁,冯世尧,徐兴欣,吴永贵.TAK1抑制剂对高糖环境巨噬细胞和系膜细胞相互作用的影响及机制[J].安徽医科大学学报,2016,51(10):1453-1458. 被引量:2
-
2张雯,张蕾,任守忠,刘日升.泼尼松龙可抑制转化生长因子β激活激酶1诱导的成骨细胞凋亡[J].中国组织工程研究,2019,23(23):3630-3635. 被引量:2
-
3左斌,邹凯,车彪,喻忠斌.泼尼松龙通过抑制TAK1诱导成骨细胞凋亡的实验研究[J].疑难病杂志,2019,0(6):610-615.
-
1覃春美,欧三桃.高磷血症与慢性肾脏病血管钙化研究进展[J].现代临床医学,2015,41(1):13-15. 被引量:5
-
2张昆,崔春黎,余晨.腹膜透析与高磷血症[J].中华肾脏病杂志,2013,29(8):627-630. 被引量:7
-
3毕礼明,朱冬云,马济佩.慢性肾衰竭高尿酸血症认识争议和中医治疗策略[J].中国中西医结合肾病杂志,2011,12(9):834-835. 被引量:5
-
4杨明根,赵晓昆.α1受体阻滞剂治疗良性前列腺增生合并高血压研究进展[J].中华男科学杂志,2007,13(9):830-834. 被引量:18
-
5饶春燕,乐湘华,赵晓晏.NF-κB与急性坏死性胰腺炎[J].重庆医学,2012,41(10):1019-1021. 被引量:3
-
6严玉澄.慢性同种移植肾功能不全进展的非免疫学危险因素[J].国外医学(泌尿系统分册),2003,23(1):23-28.
-
7胡秀芳,张高亮,杨贤强.茶多酚对肾病的作用及其机理[J].茶叶科学,2002,22(2):98-104. 被引量:13
-
8张剑,楼天正,张宁.脓毒症的肝功能障碍发病机制及诊治研究[J].中华急诊医学杂志,2014,23(10):1183-1185. 被引量:9
-
9徐亚吉,冯志强.肾小管上皮细胞转分化的信号转导途径[J].泸州医学院学报,2008,31(1):98-100. 被引量:1
-
10王珣,任伟.慢性肾脏疾病患者血管钙化治疗研究进展[J].国际移植与血液净化杂志,2013,11(6):14-17.