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拉米夫定联合胸腺肽治疗慢性乙型肝炎25例临床分析 被引量:2

The Clinical Analysis of 25 Chronic Hepatitis B Patients Treated with Lamivudine and Thymic Peptide
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摘要 目的:观察拉米夫定联合胸腺肽治疗慢性乙型肝炎的效果.方法:将50例慢性乙型肝炎病人,随机分为治疗组25例,给予拉米夫定100mg,qd疗程12月;胸腺肽160mg,每周2次,疗程6月.对照组25例,给予拉米夫定100mg,qd疗程12月.结果:治疗组总有效率88.0%;对照组总有效率56.0%,两组总有效率相比有显著差异性(x^2=6.39,P<0.05).结论:拉米夫定联合胸腺肽治疗慢性乙型肝炎疗效肯定,可作为一种有效的治疗方法. Objective: To invesitigate the clinical effects of Lamivudine and Thymic Peptide treating Chronic Hepatitis B Patients.Methods: 50 patients were divided into two groups randomly . Treatment group 25 patients were treated with Lamivudine and Thymic Peptide; Control group 25 patients were treated with Lamivudine only.Results: The effective rate was 88.0% in treatment group and 56.0% in control group. The difference was very significant between two group (X^2 = 6.39, P 〈 0.05). Conclusion Lamivudine and Thymic Peptide have significandly effects on Chronic Hepatitis B patients.
出处 《中国医药导刊》 2005年第4期286-287,共2页 Chinese Journal of Medicinal Guide
关键词 拉米夫定 联合用药 胸腺肽 药物治疗 慢性乙型肝炎 临床分析 Lamivudine Thymic Peptide Chronic Hepatitis B
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  • 1Lee W.Hepatitis B Virus Infection[J].N Engl J Med,1997,337:1733.
  • 2Hoofnagle JH,DiBisceglie AM.The treatrnent of chrnic viral hepatitis[J].N Engl J Med.1997,336:347.
  • 3Lai CL,Chien RN,Leung NWY,et al.A one -year trial of lamivudine for chronic hepatitis B[J].N Engl J Med,1998,339:61.
  • 4Sokal E,Roberta EA,Mieli-Vergani G,et al.Dose—finding and safety of Iamivudine in children and adolescents with ehronie hepatitis B(abstract)[J].Hepatology,1998,28(4pt2)489A.
  • 5Lai CI,Ching CK,Tung AKM,et a1.Lamivudine is effective in suppreasing bepatitis B virus DNA in chinese hepatitis B surface antigen carriers:a placebo-controlled trial[J].Hepatology,1997,25:241.
  • 6Allen MI,Dealauriers M,Andrews W,et a1.Identification and characterization of mutations in hepatitis B virus resistant to almivudine[J].Hepatology ,1998,27:1670.
  • 7Chayama K,Yoshiyuki S,Kobayashi M,et al,Emergence and takeover of YMDD matif matant hepatitis B virus duing long-term lamivudine therapy and re-takeover by wild type after cessation of therapy[J].Hepatology,1998.27:1711.
  • 8Niesters HGM,Honkoop P,Haagama EB,et a1.Identification of more than one mutation in the hepatitis B virus polymerase gene arising during prolonged lamivudine treatment [J].J Infect Dis,1998,177:1382.
  • 9Tipplea GA,Ma MM,Fischer KP,et al.Mutation in HBV RNA-dependent DNA polymerase confers resistance to lamivadine in vivo[J].Hepatology,1996.24:714.
  • 10Melegari M, Scaglioni PP, Wands JR,et al.Hepstitis B virus mutations associated with 3TC and Famciclovir administration are replication delective[J]. Hepatology, 1998,27:628.

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