摘要
将栖霞县1993、1994两年出生的婴儿11897人分两组。预防组生后第1天开始口服维生素K_12.5mg,15天1次共6次;对照组未用药.对两组婴儿患晚发性维生素K缺乏症的情况观察到生后5个月～1 岁,3个月内发病者统计比较,结果显示:对照组发病61例(13.84‰),预防组发病1例(0.13‰),两组比较x^2=97.90,P<0.01。说明本病在我国发病率较高,进行群体预防非常必要.口服VK_1预防无副作用,经济方便,值得推广.
A total of 11897 infants born in Qixia county in 1993 and 1994 were randomly divided into two groups: infants in prophylactic group were given an oral administration of vitamin K1 ,2. 5mg every 15 days for 6 times from the lst day after birth,infants in the control group received no vitamin K1. It was found that the incidence of Vitamin K defficiency in the infants first three months in the prophylactic group(1 case,0.13‰) was stastically lower than that in the control group(61 cases,13. 84‰)( X2 = 97. 90,P <0. 01).The results prove that oral administraton of vitamin K1 has significant prophylactic effect on vitamin K defficiency in infants and is economic with no side effect and easy to be popularized.
关键词
婴儿
维生素K缺乏症
发病率
预防
Infant Vitamin K Defficiency Incidence Prophylaxis.
