低温射频等离子术治疗阻塞性睡眠呼吸暂停综合征被引量：15

The treatment of obstructive sleep paean syndrome by the temperature-controlled radio frequency ablation

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摘要目的为了观察低温射频等离子消融术治疗单纯性鼾症或轻、中度睡眠呼吸暂停综合征的效果。方法观察了以软颚和悬雍垂后气道阻塞的鼾症-轻、中度的阻塞睡眠呼吸暂停综合征患者30例。随诊观察1个月、3个月、6个月术前及术后4周、12周、24周进行Epworth嗜睡问卷,PSG监测,纤维咽喉镜检测及评价。结果1个月显效0%,进步1%,无效99%,总有效率1%。3个月显效4%,进步52%,无效43%,总有效率56%。6个月显效48%,进步48%,无效4%,总有效率96%。低温射频等离子消融术治疗中度以下阻塞睡眠呼吸暂停综合征,目前是临床治疗中有效的疗法。手术的次数、时间与疗效有明确的相关性。结论低温射频等离子消融术与悬雍垂腭咽成形术(UPPP)比较,安全、有效、可行,术后轻微的不适和较少的副作用。认为它是一种其最小程度地引起上气道的重构,保证了神经反射弧的完整。没有UPPP手术后的并发症。停止治疗后的长期观察还有待进一步随访。 Objective A prospective non-randomized study was designed to investigate the effects of the temperature-controlled radiofrequency（TCRF） ablation on soft palate in patients with simple snoring or mild to mederate obstructive sleep apnea syndrome（OSAS）. Methods 30 ceases of simple snoring or mild to moderate OSAS were treated by TCRF ahlation. These patients were followed up at one, three and six months after TCRF ablation. They were evaluated by polysomnography（PSG）, laryngoscope,and Epworth＇s sleepiness scale in four,twelve,and twenty four weeks following TCRF. Results ①At one month following TCRF,0% was effective,l% was improved,and 99% was not effective,with a total effective rate of 1%. ② At three month following TCRF, 4% was effective, 52% was improved,and 48% was not effective, with a total effective rate of 56%. ③At six month following TCRF,48% was effective,48% was improved,and 4% was not effectlve,with a total effective rate of 96%. TCRF is effective in treatment of simple snoring and mild to moderate OSAS. The effectiveness of TCRF is definitely associated with the times and postoperative duration of the ablations. Conclusions TCRF Compared with uvular palate pharyngealplastics （UPPP）, TCRF ablation is safer,more effective and applicable with less postoperative discomfort and side effects in treatment of OSAS. TCRF could significantly reduce the degree of upper airway remodeling,protect the intact nerve reflection, and cause no postoperative complications. A longer further follow up after TCRF is still needed.

作者王实夏书月吴艺虹卢丹王谦

机构地区沈阳医学院附属中心医院呼吸内科

出处《国外医学（呼吸系统分册）》 2005年第8期563-565,共3页 Section of Respiratory System Foreign Medical Sciences

基金沈阳市科委资助项目(99-60001)

关键词低温射频等离子术手术治疗阻塞性睡眠呼吸暂停综合征悬雍垂腭咽成形术低温射频 Obstructive sleep apnea syndrome Temperature controlled radiofrequency ablation Effective rate

分类号 R766 [医药卫生—耳鼻咽喉科]

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