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垂体腺瘤的基因治疗

Gene therapy for pituitary adenomas
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作者 马驰原 史继新
机构地区 南京军区南京总医院神经外科
出处 《中华神经医学杂志》 CAS CSCD 2005年第8期855-857,共3页 Chinese Journal of Neuromedicine
关键词 垂体肿瘤 基因疗法 Pituitary neoplasms Gene therapy
分类号 R736.4 [医药卫生—肿瘤]
  • 相关文献

参考文献15

  • 1Castro MG. Gene therapy strategies for the treatment of pituitary tumours[J]. J Mol Endocrinol, 1999, 22(1): 9-18.
  • 2Castro MG, Goya RG, Sosa YE, et al. Expression of transgenes in normal and neoplastic anterior pituitary cells using recombinant adenoviruses: long term expression, cell cycle dependency, and effects on hormone secretion [J]. Endocrinology, 1997, 138 (5):2184-2194.
  • 3Windeatt S, Southgate TD, Dewey RA, et al. Adenovirus-mediated herpes simplex virus type-1 thymidine kinase gene therapy suppresses oestrogen-induced pituitary prolactinomas [J]. J Clin Endocrinol Metab, 2000, 85(3): 1296-1305.
  • 4Bolognani F, Goya RG. Gene therapy in the neuroendocrine system:its implementation in experimental models using viral vectors [J].Neuroendocrinology, 2001, 73(2): 75-83.
  • 5Frost S J, Simpson DJ, Clayton RN, et al. Transfection of an inducible p16/CDKN2A construct mediates reversible growth inhibition and G1 arrest in the AtT20 pituitary tumor cell line[J]. Mol Endocrinol,1999, 13(11): 1801-1810.
  • 6Freese A, During MJ, Davidson BL, et al. Transfection of human lactotroph adenoma cells with an adenovirus vector expressing tyrosine hydroxylase decreases prolactin release[J]. J Clin Endocrinol Metab, 1996, 81 (6): 2401-2404.
  • 7Castro MG, Windeatt S, Smith-Arica J, et al. Cell-type specific expression in the pituitary: physiology and gene therapy[J]. Biochem Soc Trans, 1999, 27(6): 858-863.
  • 8Goya RG, Rowe J, Sosa YE, et al. Use of recombinant herpes simplex virus type vectors for gene transfer into tumors and normal anterior pituitary cells [J]. Mol Cell Endocrinol, 1998, 139(1-2):199-207.
  • 9Lee E J, Anderson LM, Thimmapaya B, et al. Targeted expression of toxic genes directed by pituitary hormone promoters: a potential strategy for adenovirus-mediated gene therapy of pituitary tumors[J].J Clin Endocrinol Metab, 1999, 84(2): 786-794.
  • 10Lee E J, Martinson F, Kotlar T, et al. Adenovirus-mediated targeted expression of toxic genes to adrenocorticotropin-producing pituitary tumors using the proopiomelanocortin promoter [J]. J Clin Endocrinol Metab, 2001, 86(7): 3400-3409.

二级参考文献22

  • 1Molitch ME. Medical treatment of prolactinomas.Endocrinol Metab Clin North Am, 1999, 28(1):143-169.
  • 2Brown ER, Coker GT, O' Malley KL. Organization and evolution of the rat tyrosine hydroxylase gene. Biochemistry,1987, 26(16):5208-5212.
  • 3Freese A, During M J, Davidson BL, et al. Transfection of human lactotroph adenoma cells with an adenovirus vector expressing tyrosine hydroxylase decreases prolactin release.J Clin Endocrinol Metab, 1996, 81(6):2401-2404.
  • 4He TC, Zhou SB, Costar LTD, et al. A simplified system for generating recombinant adenovirus. Proc Nail Acad Sci USA, 1998, 95(5):2509-2514.
  • 5Colao A, Annunziato L, Lombardi G. Treatment of prolactinomas. Ann Med, 1998, 30(5):452-459.
  • 6Tyrrell JB, Lambom KR, Hannegan LT, et al. Transsphenoidal microsurgical therapy of prolactinomas: initial outcomes and long-term results. Neurosurgey, 1999, 44(2):254-263.
  • 7During M J, Naegele JR, O' Malley KL, et al. Long-term behavioral recovery in Parkinsonian rats by an HSV vector expressing tyrosine hydroxylase. Science, 1994, 266(25):1399-1403.
  • 8Moffat M, Harmon S, Haycock J, et al. L-dopa and dopamine-producing gene cassettes for gene therapy approaches to Parkinson's disease. Exp Neurol, 1997, 144(1):69-73.
  • 9Windeatt S, Southgate TD, Dewey RA, et al. Adenovirusmediated herpes simplex virus type-1 thymidine kinase gene therapy suppresses oestrogen-induced pituitary prolactinomas.J Clin Endocrinol Metab, 2000, 85(3):1296-1305.
  • 10Neill JD, Musgrove LC, Duck LW, et al. High efficiency method for gene transfer in normal pituitary gonadotropes:adenoviral-mediated expression of G protein-coupled receptor kinase 2 suppresses luteinizing hormone secretion. Endocrinology, 1999, 140(6):2562-2569.

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中华神经医学杂志
2005年 第8期

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